Conley PB - Search Results

1

Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling.

Nanda N, Andre P, Bao M, Clauser K, Deguzman F, Howie D, Conley PB, Terhorst C, Phillips DR. Nanda N, et al. Among authors: conley pb. Blood. 2005 Nov 1;106(9):3028-34. doi: 10.1182/blood-2005-01-0333. Epub 2005 Jul 21. Blood. 2005. PMID: 16037392 Free article.

2

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries.

Andre P, Delaney SM, LaRocca T, Vincent D, DeGuzman F, Jurek M, Koller B, Phillips DR, Conley PB. Andre P, et al. Among authors: conley pb. J Clin Invest. 2003 Aug;112(3):398-406. doi: 10.1172/JCI17864. J Clin Invest. 2003. PMID: 12897207 Free PMC article.

3

Therapeutic approaches in arterial thrombosis.

Phillips DR, Conley PB, Sinha U, Andre P. Phillips DR, et al. Among authors: conley pb. J Thromb Haemost. 2005 Aug;3(8):1577-89. doi: 10.1111/j.1538-7836.2005.01418.x. J Thromb Haemost. 2005. PMID: 16102022 Free article. Review.

4

Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.

André P, LaRocca T, Delaney SM, Lin PH, Vincent D, Sinha U, Conley PB, Phillips DR. André P, et al. Among authors: conley pb. Circulation. 2003 Nov 25;108(21):2697-703. doi: 10.1161/01.CIR.0000093279.36628.12. Epub 2003 Nov 3. Circulation. 2003. PMID: 14597584

5

Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation.

Nanda N, Bao M, Lin H, Clauser K, Komuves L, Quertermous T, Conley PB, Phillips DR, Hart MJ. Nanda N, et al. Among authors: conley pb. J Biol Chem. 2005 Jul 1;280(26):24680-9. doi: 10.1074/jbc.M413411200. Epub 2005 Apr 25. J Biol Chem. 2005. PMID: 15851471 Free article.

6

Thienopyridines, but not elinogrel, result in off-target effects at the vessel wall that contribute to bleeding.

André P, DeGuzman F, Haberstock-Debic H, Mills S, Pak Y, Inagaki M, Pandey A, Hollenbach S, Phillips DR, Conley PB. André P, et al. Among authors: conley pb. J Pharmacol Exp Ther. 2011 Jul;338(1):22-30. doi: 10.1124/jpet.110.178574. Epub 2011 Mar 29. J Pharmacol Exp Ther. 2011. PMID: 21447613

7

A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist.

Haberstock-Debic H, Andre P, Mills S, Phillips DR, Conley PB. Haberstock-Debic H, et al. Among authors: conley pb. J Pharmacol Exp Ther. 2011 Oct;339(1):54-61. doi: 10.1124/jpet.111.184143. Epub 2011 Jul 5. J Pharmacol Exp Ther. 2011. PMID: 21730013

8

Development of a perfusion chamber assay to study in real time the kinetics of thrombosis and the antithrombotic characteristics of antiplatelet drugs.

Stephens G, He M, Wong C, Jurek M, Luedemann HC, Shapurian G, Munnelly K, Muir C, Conley PB, Phillips DR, Andre P. Stephens G, et al. Among authors: conley pb. Thromb J. 2012 Aug 1;10(1):11. doi: 10.1186/1477-9560-10-11. Thromb J. 2012. PMID: 22852789 Free PMC article.

9

A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa.

Lu G, DeGuzman FR, Hollenbach SJ, Karbarz MJ, Abe K, Lee G, Luan P, Hutchaleelaha A, Inagaki M, Conley PB, Phillips DR, Sinha U. Lu G, et al. Among authors: conley pb. Nat Med. 2013 Apr;19(4):446-51. doi: 10.1038/nm.3102. Epub 2013 Mar 3. Nat Med. 2013. PMID: 23455714

10

Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model.

Lu G, Pine P, Leeds JM, DeGuzman F, Pratikhya P, Lin J, Malinowski J, Hollenbach SJ, Curnutte JT, Conley PB. Lu G, et al. Among authors: conley pb. PLoS One. 2018 Mar 28;13(3):e0195122. doi: 10.1371/journal.pone.0195122. eCollection 2018. PLoS One. 2018. PMID: 29590221 Free PMC article.

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