Eriksen J - Search Results

1

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.

McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, DeLucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T. McGowan E, et al. Among authors: eriksen j. Neuron. 2005 Jul 21;47(2):191-199. doi: 10.1016/j.neuron.2005.06.030. Neuron. 2005. PMID: 16039562 Free PMC article.

2

Caught in the act: alpha-synuclein is the culprit in Parkinson's disease.

Eriksen JL, Dawson TM, Dickson DW, Petrucelli L. Eriksen JL, et al. Neuron. 2003 Oct 30;40(3):453-6. doi: 10.1016/s0896-6273(03)00684-6. Neuron. 2003. PMID: 14642269 Free article. Review.

3

A decade of modeling Alzheimer's disease in transgenic mice.

McGowan E, Eriksen J, Hutton M. McGowan E, et al. Among authors: eriksen j. Trends Genet. 2006 May;22(5):281-9. doi: 10.1016/j.tig.2006.03.007. Epub 2006 Mar 29. Trends Genet. 2006. PMID: 16567017 Review.

4

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production.

Kukar T, Murphy MP, Eriksen JL, Sagi SA, Weggen S, Smith TE, Ladd T, Khan MA, Kache R, Beard J, Dodson M, Merit S, Ozols VV, Anastasiadis PZ, Das P, Fauq A, Koo EH, Golde TE. Kukar T, et al. Among authors: eriksen jl. Nat Med. 2005 May;11(5):545-50. doi: 10.1038/nm1235. Epub 2005 Apr 17. Nat Med. 2005. PMID: 15834426

5

Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.

Kukar T, Prescott S, Eriksen JL, Holloway V, Murphy MP, Koo EH, Golde TE, Nicolle MM. Kukar T, et al. BMC Neurosci. 2007 Jul 24;8:54. doi: 10.1186/1471-2202-8-54. BMC Neurosci. 2007. PMID: 17650315 Free PMC article.

6

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.

Eriksen JL, Sagi SA, Smith TE, Weggen S, Das P, McLendon DC, Ozols VV, Jessing KW, Zavitz KH, Koo EH, Golde TE. Eriksen JL, et al. J Clin Invest. 2003 Aug;112(3):440-9. doi: 10.1172/JCI18162. J Clin Invest. 2003. PMID: 12897211 Free PMC article.

7

Development of a high throughput drug screening assay for the detection of changes in tau levels -- proof of concept with HSP90 inhibitors.

Dickey CA, Eriksen J, Kamal A, Burrows F, Kasibhatla S, Eckman CB, Hutton M, Petrucelli L. Dickey CA, et al. Among authors: eriksen j. Curr Alzheimer Res. 2005 Apr;2(2):231-8. doi: 10.2174/1567205053585927. Curr Alzheimer Res. 2005. PMID: 15974923

8

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.

Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. Weggen S, et al. Among authors: eriksen jl. Nature. 2001 Nov 8;414(6860):212-6. doi: 10.1038/35102591. Nature. 2001. PMID: 11700559

9

Substrate-targeting gamma-secretase modulators.

Kukar TL, Ladd TB, Bann MA, Fraering PC, Narlawar R, Maharvi GM, Healy B, Chapman R, Welzel AT, Price RW, Moore B, Rangachari V, Cusack B, Eriksen J, Jansen-West K, Verbeeck C, Yager D, Eckman C, Ye W, Sagi S, Cottrell BA, Torpey J, Rosenberry TL, Fauq A, Wolfe MS, Schmidt B, Walsh DM, Koo EH, Golde TE. Kukar TL, et al. Among authors: eriksen j. Nature. 2008 Jun 12;453(7197):925-9. doi: 10.1038/nature07055. Nature. 2008. PMID: 18548070 Free PMC article.

10

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17.

Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S, Cannon A, Dwosh E, Neary D, Melquist S, Richardson A, Dickson D, Berger Z, Eriksen J, Robinson T, Zehr C, Dickey CA, Crook R, McGowan E, Mann D, Boeve B, Feldman H, Hutton M. Baker M, et al. Among authors: eriksen j. Nature. 2006 Aug 24;442(7105):916-9. doi: 10.1038/nature05016. Epub 2006 Jul 16. Nature. 2006. PMID: 16862116

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