Vornov J - Search Results

1

The central nervous system effects, pharmacokinetics and safety of the NAALADase-inhibitor GPI 5693.

van der Post JP, de Visser SJ, de Kam ML, Woelfler M, Hilt DC, Vornov J, Burak ES, Bortey E, Slusher BS, Limsakun T, Cohen AF, van Gerven JM. van der Post JP, et al. Among authors: vornov j. Br J Clin Pharmacol. 2005 Aug;60(2):128-36. doi: 10.1111/j.1365-2125.2005.02396.x. Br J Clin Pharmacol. 2005. PMID: 16042665 Free PMC article. Clinical Trial.

2

Pharmacokinetics and pharmacodynamics of the glutamate carboxypeptidase II inhibitor 2-MPPA show prolonged alleviation of neuropathic pain through an indirect mechanism.

Vornov JJ, Wozniak KM, Wu Y, Rojas C, Rais R, Slusher BS. Vornov JJ, et al. J Pharmacol Exp Ther. 2013 Sep;346(3):406-13. doi: 10.1124/jpet.113.205039. Epub 2013 Jun 17. J Pharmacol Exp Ther. 2013. PMID: 23776202 Free PMC article.

3

The orally active glutamate carboxypeptidase II inhibitor E2072 exhibits sustained nerve exposure and attenuates peripheral neuropathy.

Wozniak KM, Wu Y, Vornov JJ, Lapidus R, Rais R, Rojas C, Tsukamoto T, Slusher BS. Wozniak KM, et al. Among authors: vornov jj. J Pharmacol Exp Ther. 2012 Dec;343(3):746-54. doi: 10.1124/jpet.112.197665. Epub 2012 Sep 17. J Pharmacol Exp Ther. 2012. PMID: 22988061

4

Ghrelin agonist HM01 attenuates chemotherapy-induced neurotoxicity in rodent models.

Chiorazzi A, Wozniak KM, Rais R, Wu Y, Gadiano AJ, Farah MH, Liu Y, Canta A, Alberti P, Rodriguez-Menendez V, Meregalli C, Fumagalli G, Monza L, Pozzi E, Vornov JJ, Polydefkis M, Pietra C, Slusher BS, Cavaletti G. Chiorazzi A, et al. Among authors: vornov jj. Eur J Pharmacol. 2018 Dec 5;840:89-103. doi: 10.1016/j.ejphar.2018.09.029. Epub 2018 Sep 27. Eur J Pharmacol. 2018. PMID: 30268665

5

Toxicity induced by a polyglutamated folate analog is attenuated by NAALADase inhibition.

Thomas AG, Olkowski JL, Vornov JJ, Slusher BS. Thomas AG, et al. Among authors: vornov jj. Brain Res. 1999 Oct 2;843(1-2):48-52. doi: 10.1016/s0006-8993(99)01879-x. Brain Res. 1999. PMID: 10528109

6

N-Acetylated alpha-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin.

Thomas AG, Vornov JJ, Olkowski JL, Merion AT, Slusher BS. Thomas AG, et al. Among authors: vornov jj. J Pharmacol Exp Ther. 2000 Oct;295(1):16-22. J Pharmacol Exp Ther. 2000. PMID: 10991955

7

Gastrointestinal delivery of propofol from fospropofol: its bioavailability and activity in rodents and human volunteers.

Wozniak KM, Vornov JJ, Mistry BM, Wu Y, Rais R, Slusher BS. Wozniak KM, et al. Among authors: vornov jj. J Transl Med. 2015 May 29;13:170. doi: 10.1186/s12967-015-0526-9. J Transl Med. 2015. PMID: 26021605 Free PMC article. Clinical Trial.

8

Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy.

Thomas AG, Wozniak KM, Tsukamoto T, Calvin D, Wu Y, Rojas C, Vornov J, Slusher BS. Thomas AG, et al. Among authors: vornov j. Adv Exp Med Biol. 2006;576:327-37; discussion 361-3. doi: 10.1007/0-387-30172-0_24. Adv Exp Med Biol. 2006. PMID: 16802724 Review.

9

Pharmacokinetics and pharmacodynamics of the new propofol prodrug GPI 15715 in rats.

Schywalsky M, Ihmsen H, Tzabazis A, Fechner J, Burak E, Vornov J, Schwilden H. Schywalsky M, et al. Among authors: vornov j. Eur J Anaesthesiol. 2003 Mar;20(3):182-90. doi: 10.1017/s0265021503000322. Eur J Anaesthesiol. 2003. Retraction in: Eur J Anaesthesiol. 2010 Apr;27(4):402. doi: 10.1097/EJA.0b013e3283389f5c PMID: 12650488 Retracted.

10

Looking for Drugs in All the Wrong Places: Use of GCPII Inhibitors Outside the Brain.

Vornov JJ, Peters D, Nedelcovych M, Hollinger K, Rais R, Slusher BS. Vornov JJ, et al. Neurochem Res. 2020 Jun;45(6):1256-1267. doi: 10.1007/s11064-019-02909-y. Epub 2019 Nov 20. Neurochem Res. 2020. PMID: 31749072 Free PMC article. Review.

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