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Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production.
Coll AP, Fassnacht M, Klammer S, Hahner S, Schulte DM, Piper S, Tung YC, Challis BG, Weinstein Y, Allolio B, O'Rahilly S, Beuschlein F. Coll AP, et al. Among authors: piper s. J Endocrinol. 2006 Aug;190(2):515-25. doi: 10.1677/joe.1.06749. J Endocrinol. 2006. PMID: 16899584 Free PMC article.
Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance.
Mountjoy KG, Caron A, Hubbard K, Shome A, Grey AC, Sun B, Bould S, Middleditch M, Pontré B, McGregor A, Harris PWR, Kowalczyk R, Brimble MA, Botha R, Tan KML, Piper SJ, Buchanan C, Lee S, Coll AP, Elmquist JK. Mountjoy KG, et al. Among authors: piper sj. Mol Metab. 2018 Mar;9:207-216. doi: 10.1016/j.molmet.2017.11.008. Epub 2017 Nov 24. Mol Metab. 2018. PMID: 29226825 Free PMC article.
Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin.
Piper SJ, Brillault L, Rothnagel R, Croll TI, Box JK, Chassagnon I, Scherer S, Goldie KN, Jones SA, Schepers F, Hartley-Tassell L, Ve T, Busby JN, Dalziel JE, Lott JS, Hankamer B, Stahlberg H, Hurst MRH, Landsberg MJ. Piper SJ, et al. Nat Commun. 2019 Apr 26;10(1):1952. doi: 10.1038/s41467-019-09890-8. Nat Commun. 2019. PMID: 31028251 Free PMC article.
Structure and dynamics of the active Gs-coupled human secretin receptor.
Dong M, Deganutti G, Piper SJ, Liang YL, Khoshouei M, Belousoff MJ, Harikumar KG, Reynolds CA, Glukhova A, Furness SGB, Christopoulos A, Danev R, Wootten D, Sexton PM, Miller LJ. Dong M, et al. Nat Commun. 2020 Aug 18;11(1):4137. doi: 10.1038/s41467-020-17791-4. Nat Commun. 2020. PMID: 32811827 Free PMC article.
402 results