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Tacrolimus suppresses glucose-induced insulin release from pancreatic islets by reducing glucokinase activity.
Radu RG, Fujimoto S, Mukai E, Takehiro M, Shimono D, Nabe K, Shimodahira M, Kominato R, Aramaki Y, Nishi Y, Funakoshi S, Yamada Y, Seino Y. Radu RG, et al. Among authors: fujimoto s. Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E365-71. doi: 10.1152/ajpendo.00390.2004. Epub 2004 Oct 12. Am J Physiol Endocrinol Metab. 2005. PMID: 15479952 Free article.
Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.
Takehiro M, Fujimoto S, Shimodahira M, Shimono D, Mukai E, Nabe K, Radu RG, Kominato R, Aramaki Y, Seino Y, Yamada Y. Takehiro M, et al. Among authors: fujimoto s. Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E372-80. doi: 10.1152/ajpendo.00157.2004. Epub 2004 Oct 12. Am J Physiol Endocrinol Metab. 2005. PMID: 15479955 Free article.
A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement.
Sassa M, Fukuda K, Fujimoto S, Toyoda K, Fujita Y, Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Ohara T, Okamoto M, Tanaka K, Seino Y, Inagaki N, Yamada Y. Sassa M, et al. Among authors: fujimoto s. Diabetes Res Clin Pract. 2006 Sep;73(3):235-40. doi: 10.1016/j.diabres.2006.01.012. Epub 2006 Apr 5. Diabetes Res Clin Pract. 2006. PMID: 16600414 Clinical Trial.
SUIT, secretory units of islets in transplantation: An index for therapeutic management of islet transplanted patients and its application to type 2 diabetes.
Yamada Y, Fukuda K, Fujimoto S, Hosokawa M, Tsukiyama K, Nagashima K, Fukushima M, Suzuki H, Toyoda K, Sassa M, Funakoshi S, Inagaki N, Taniguchi A, Sato TS, Matsumoto S, Tanaka K, Seino Y. Yamada Y, et al. Among authors: fujimoto s. Diabetes Res Clin Pract. 2006 Dec;74(3):222-6. doi: 10.1016/j.diabres.2006.03.030. Epub 2006 May 16. Diabetes Res Clin Pract. 2006. PMID: 16707190
Adult pancreatic islets require differential pax6 gene dosage.
Hamasaki A, Yamada Y, Kurose T, Ban N, Nagashima K, Takahashi A, Fujimoto S, Shimono D, Fujiwara M, Toyokuni S, Seino Y, Inagaki N. Hamasaki A, et al. Among authors: fujimoto s. Biochem Biophys Res Commun. 2007 Feb 2;353(1):40-6. doi: 10.1016/j.bbrc.2006.11.105. Epub 2006 Dec 4. Biochem Biophys Res Commun. 2007. PMID: 17178107
2,747 results