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Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus.
Wells KD, Bardot R, Whitworth KM, Trible BR, Fang Y, Mileham A, Kerrigan MA, Samuel MS, Prather RS, Rowland RRR. Wells KD, et al. Among authors: kerrigan ma. J Virol. 2017 Jan 3;91(2):e01521-16. doi: 10.1128/JVI.01521-16. Print 2017 Jan 15. J Virol. 2017. PMID: 27847356 Free PMC article.
An intact sialoadhesin (Sn/SIGLEC1/CD169) is not required for attachment/internalization of the porcine reproductive and respiratory syndrome virus.
Prather RS, Rowland RR, Ewen C, Trible B, Kerrigan M, Bawa B, Teson JM, Mao J, Lee K, Samuel MS, Whitworth KM, Murphy CN, Egen T, Green JA. Prather RS, et al. Among authors: kerrigan m. J Virol. 2013 Sep;87(17):9538-46. doi: 10.1128/JVI.00177-13. Epub 2013 Jun 19. J Virol. 2013. PMID: 23785195 Free PMC article.
Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus.
Whitworth KM, Rowland RR, Ewen CL, Trible BR, Kerrigan MA, Cino-Ozuna AG, Samuel MS, Lightner JE, McLaren DG, Mileham AJ, Wells KD, Prather RS. Whitworth KM, et al. Among authors: kerrigan ma. Nat Biotechnol. 2016 Jan;34(1):20-2. doi: 10.1038/nbt.3434. Epub 2015 Dec 7. Nat Biotechnol. 2016. PMID: 26641533 No abstract available.
84 results