Deaciuc AG - Search Results

1

Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands.

Zheng G, Dwoskin LP, Deaciuc AG, Crooks PA. Zheng G, et al. Among authors: deaciuc ag. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4463-6. doi: 10.1016/j.bmcl.2005.07.032. Bioorg Med Chem Lett. 2005. PMID: 16112864 Free PMC article.

2

Structural modifications to tetrahydropyridine-3-carboxylate esters en route to the discovery of M5-preferring muscarinic receptor orthosteric antagonists.

Zheng G, Smith AM, Huang X, Subramanian KL, Siripurapu KB, Deaciuc A, Zhan CG, Dwoskin LP. Zheng G, et al. J Med Chem. 2013 Feb 28;56(4):1693-703. doi: 10.1021/jm301774u. Epub 2013 Feb 18. J Med Chem. 2013. PMID: 23379472 Free PMC article.

3

Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters.

Hojahmat M, Horton DB, Norrholm SD, Miller DK, Grinevich VP, Deaciuc AG, Dwoskin LP, Crooks PA. Hojahmat M, et al. Among authors: deaciuc ag. Bioorg Med Chem. 2010 Jan 15;18(2):640-9. doi: 10.1016/j.bmc.2009.12.002. Epub 2009 Dec 6. Bioorg Med Chem. 2010. PMID: 20036131 Free PMC article.

4

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2.

Zheng G, Dwoskin LP, Deaciuc AG, Zhu J, Jones MD, Crooks PA. Zheng G, et al. Among authors: deaciuc ag. Bioorg Med Chem. 2005 Jun 2;13(12):3899-909. doi: 10.1016/j.bmc.2005.04.013. Bioorg Med Chem. 2005. PMID: 15911306 Free PMC article.

5

Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.

Zheng G, Dwoskin LP, Deaciuc AG, Norrholm SD, Crooks PA. Zheng G, et al. Among authors: deaciuc ag. J Med Chem. 2005 Aug 25;48(17):5551-60. doi: 10.1021/jm0501228. J Med Chem. 2005. PMID: 16107155 Free PMC article.

6

Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity.

Sumithran SP, Crooks PA, Xu R, Zhu J, Deaciuc AG, Wilkins LH, Dwoskin LP. Sumithran SP, et al. Among authors: deaciuc ag. AAPS J. 2005 Aug 29;7(1):E201-17. doi: 10.1208/aapsj070119. AAPS J. 2005. PMID: 16146341 Free PMC article.

7

Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters.

Zheng G, Horton DB, Deaciuc AG, Dwoskin LP, Crooks PA. Zheng G, et al. Among authors: deaciuc ag. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5018-21. doi: 10.1016/j.bmcl.2006.07.070. Epub 2006 Aug 14. Bioorg Med Chem Lett. 2006. PMID: 16905316 Free PMC article.

8

N, N -disubstituted piperazines and homopiperazines: synthesis and affinities at alpha4beta2* and alpha7* neuronal nicotinic acetylcholine receptors.

Chen J, Deaciuc AG, Dwoskin LP, Crooks PA, Bai D. Chen J, et al. Among authors: deaciuc ag. J Enzyme Inhib Med Chem. 2006 Dec;21(6):667-80. doi: 10.1080/14756360600900513. J Enzyme Inhib Med Chem. 2006. PMID: 17252939 Free article.

9

Tris-azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

Zheng G, Sumithran SP, Deaciuc AG, Dwoskin LP, Crooks PA. Zheng G, et al. Among authors: deaciuc ag. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6701-6. doi: 10.1016/j.bmcl.2007.10.062. Epub 2007 Oct 22. Bioorg Med Chem Lett. 2007. PMID: 17977723 Free PMC article.

10

Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation.

Zheng G, Zhang Z, Pivavarchyk M, Deaciuc AG, Dwoskin LP, Crooks PA. Zheng G, et al. Among authors: deaciuc ag. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6734-8. doi: 10.1016/j.bmcl.2007.10.052. Epub 2007 Oct 18. Bioorg Med Chem Lett. 2007. PMID: 18029180 Free PMC article.

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