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Intranasal immunization with a formalin-inactivated human influenza A virus whole-virion vaccine alone and intranasal immunization with a split-virion vaccine with mucosal adjuvants show similar levels of cross-protection.
Okamoto S, Matsuoka S, Takenaka N, Haredy AM, Tanimoto T, Gomi Y, Ishikawa T, Akagi T, Akashi M, Okuno Y, Mori Y, Yamanishi K. Okamoto S, et al. Among authors: tanimoto t. Clin Vaccine Immunol. 2012 Jul;19(7):979-90. doi: 10.1128/CVI.00016-12. Epub 2012 May 2. Clin Vaccine Immunol. 2012. PMID: 22552600 Free PMC article.
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