Schmeiser HH - Search Results

1

The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen.

Stiborová M, Sopko B, Hodek P, Frei E, Schmeiser HH, Hudecek J. Stiborová M, et al. Among authors: schmeiser hh. Cancer Lett. 2005 Nov 18;229(2):193-204. doi: 10.1016/j.canlet.2005.06.038. Epub 2005 Aug 24. Cancer Lett. 2005. PMID: 16125300

2

Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy.

Stiborová M, Frei E, Sopko B, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: schmeiser hh. Carcinogenesis. 2002 Apr;23(4):617-25. doi: 10.1093/carcin/23.4.617. Carcinogenesis. 2002. PMID: 11960915

3

Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

Stiborová M, Frei E, Sopko B, Sopková K, Marková V, Lanková M, Kumstýrová T, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: schmeiser hh. Carcinogenesis. 2003 Oct;24(10):1695-703. doi: 10.1093/carcin/bgg119. Epub 2003 Jul 17. Carcinogenesis. 2003. PMID: 12869422

4

Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.

Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E, Stiborová M. Miksanová M, et al. Among authors: schmeiser hh. Chem Res Toxicol. 2004 May;17(5):663-71. doi: 10.1021/tx0499721. Chem Res Toxicol. 2004. PMID: 15144223

5

Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

Stiborová M, Frei E, Hodek P, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: schmeiser hh. Int J Cancer. 2005 Jan 10;113(2):189-97. doi: 10.1002/ijc.20564. Int J Cancer. 2005. PMID: 15386410

6

Identification of a genotoxic mechanism for the carcinogenicity of the environmental pollutant and suspected human carcinogen o-anisidine.

Stiborová M, Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E. Stiborová M, et al. Among authors: schmeiser hh. Int J Cancer. 2005 Sep 20;116(5):667-78. doi: 10.1002/ijc.21122. Int J Cancer. 2005. PMID: 15828049

7

The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase.

Stiborová M, Dracínská H, Hájková J, Kaderábková P, Frei E, Schmeiser HH, Soucek P, Phillips DH, Arlt VM. Stiborová M, et al. Among authors: schmeiser hh. Drug Metab Dispos. 2006 Aug;34(8):1398-405. doi: 10.1124/dmd.106.009373. Epub 2006 May 19. Drug Metab Dispos. 2006. PMID: 16714372

8

Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450.

Dracínska H, Miksanová M, Svobodová M, Smrcek S, Frei E, Schmeiser HH, Stiborová M. Dracínska H, et al. Among authors: schmeiser hh. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:9-13. Neuro Endocrinol Lett. 2006. PMID: 17159769

9

Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

Stiborová M, Martínek V, Schmeiser HH, Frei E. Stiborová M, et al. Among authors: schmeiser hh. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:35-9. Neuro Endocrinol Lett. 2006. PMID: 17159775

10

Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.

Stiborová M, Frei E, Arlt VM, Schmeiser HH. Stiborová M, et al. Among authors: schmeiser hh. Mutat Res. 2008 Jan-Feb;658(1-2):55-67. doi: 10.1016/j.mrrev.2007.07.003. Epub 2007 Aug 6. Mutat Res. 2008. PMID: 17851120 Free article. Review.

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