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CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Luo G, Cunningham M, Kim S, Burn T, Lin J, Sinz M, Hamilton G, Rizzo C, Jolley S, Gilbert D, Downey A, Mudra D, Graham R, Carroll K, Xie J, Madan A, Parkinson A, Christ D, Selling B, LeCluyse E, Gan LS. Luo G, et al. Drug Metab Dispos. 2002 Jul;30(7):795-804. doi: 10.1124/dmd.30.7.795. Drug Metab Dispos. 2002. PMID: 12065438
Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes.
Madan A, Graham RA, Carroll KM, Mudra DR, Burton LA, Krueger LA, Downey AD, Czerwinski M, Forster J, Ribadeneira MD, Gan LS, LeCluyse EL, Zech K, Robertson P Jr, Koch P, Antonian L, Wagner G, Yu L, Parkinson A. Madan A, et al. Among authors: graham ra. Drug Metab Dispos. 2003 Apr;31(4):421-31. doi: 10.1124/dmd.31.4.421. Drug Metab Dispos. 2003. PMID: 12642468
Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker-driven precision dosing.
Oni-Orisan A, Srinivas N, Mehta K, Das JL, Nguyen TT, Tison GH, Bauer SR, Burian M, Funk RS, Graham RA; Biomarkers and Translational Tools Community Working Group of the American Society for Clinical Pharmacology and Therapeutics. Oni-Orisan A, et al. Among authors: graham ra. Clin Transl Sci. 2021 May;14(3):784-790. doi: 10.1111/cts.12973. Epub 2021 Feb 12. Clin Transl Sci. 2021. PMID: 33421282 Free PMC article.
105 results