Silver IS - Search Results

1

Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.

Smith CM, Graham RA, Krol WL, Silver IS, Negishi M, Wang H, Lecluyse EL. Smith CM, et al. Among authors: silver is. J Pharmacol Exp Ther. 2005 Dec;315(3):1256-64. doi: 10.1124/jpet.105.090795. Epub 2005 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 16135700

2

Temporal kinetics and concentration-response relationships for induction of CYP1A, CYP2B, and CYP3A in primary cultures of beagle dog hepatocytes.

Graham RA, Tyler LO, Krol WL, Silver IS, Webster LO, Clark P, Chen L, Banks T, LeCluyse EL. Graham RA, et al. Among authors: silver is. J Biochem Mol Toxicol. 2006;20(2):69-78. doi: 10.1002/jbt.20118. J Biochem Mol Toxicol. 2006. PMID: 16615094

3

Metabolic activation of pioglitazone identified from rat and human liver microsomes and freshly isolated hepatocytes.

Baughman TM, Graham RA, Wells-Knecht K, Silver IS, Tyler LO, Wells-Knecht M, Zhao Z. Baughman TM, et al. Among authors: silver is. Drug Metab Dispos. 2005 Jun;33(6):733-8. doi: 10.1124/dmd.104.002683. Epub 2005 Mar 11. Drug Metab Dispos. 2005. PMID: 15764718

4

Role of ADME characteristics in drug discovery and their in silico evaluation: in silico screening of chemicals for their metabolic stability.

Gombar VK, Silver IS, Zhao Z. Gombar VK, et al. Among authors: silver is. Curr Top Med Chem. 2003;3(11):1205-25. doi: 10.2174/1568026033452014. Curr Top Med Chem. 2003. PMID: 12769701 Review.

5

Characterization of in vitro metabolites from human liver microsomes using directly coupled hplc-nmr: application to a phenoxathiin monoamine oxidase-A inhibitor.

Shockcor JP, Silver IS, Wurm RM, Sanderson PN, Farrant RD, Sweatman BC, Lindon JC. Shockcor JP, et al. Among authors: silver is. Xenobiotica. 1996 Jan;26(1):41-8. doi: 10.3109/00498259609046687. Xenobiotica. 1996. PMID: 8851820

6

Automated quantitative and qualitative analysis of metabolic stability: a process for compound selection during drug discovery.

Wring SA, Silver IS, Serabjit-Singh CJ. Wring SA, et al. Among authors: silver is. Methods Enzymol. 2002;357:285-95. doi: 10.1016/s0076-6879(02)57686-2. Methods Enzymol. 2002. PMID: 12424918 No abstract available.

7

The toxicokinetics of (1R, cis)- and (1R, trans)- tetramethrin in the isolated perfused rat liver.

Silver IS, Dauterman WC. Silver IS, et al. Xenobiotica. 1989 May;19(5):509-19. doi: 10.3109/00498258909042290. Xenobiotica. 1989. PMID: 2750207

8

The pharmacokinetics and metabolism of (1R, cis)- and (1R, trans)-tetramethrin in rats.

Silver IS, Dauterman WC. Silver IS, et al. Xenobiotica. 1989 Mar;19(3):301-14. doi: 10.3109/00498258909042275. Xenobiotica. 1989. PMID: 2665326

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