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A GC-MS/MS method for the quantitative analysis of low levels of the tyrosine metabolites maleylacetone, succinylacetone, and the tyrosine metabolism inhibitor dichloroacetate in biological fluids and tissues.
Zolodz MD, Jia M, Liu H, Henderson GN, Stacpoole PW. Zolodz MD, et al. Among authors: stacpoole pw. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jun 6;837(1-2):125-32. doi: 10.1016/j.jchromb.2006.04.027. Epub 2006 May 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16713404
Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate.
Shroads AL, Langaee T, Coats BS, Kurtz TL, Bullock JR, Weithorn D, Gong Y, Wagner DA, Ostrov DA, Johnson JA, Stacpoole PW. Shroads AL, et al. Among authors: stacpoole pw. J Clin Pharmacol. 2012 Jun;52(6):837-49. doi: 10.1177/0091270011405664. Epub 2011 Jun 3. J Clin Pharmacol. 2012. PMID: 21642471 Free PMC article.
Pharmacokinetics of oral dichloroacetate in dogs.
Maisenbacher HW 3rd, Shroads AL 3rd, Zhong G, Daigle AD, Abdelmalak MM, Samper IS, Mincey BD, James MO, Stacpoole PW. Maisenbacher HW 3rd, et al. Among authors: stacpoole pw. J Biochem Mol Toxicol. 2013 Dec;27(12):522-5. doi: 10.1002/jbt.21518. Epub 2013 Sep 13. J Biochem Mol Toxicol. 2013. PMID: 24038869
Pharmacogenetic considerations with dichloroacetate dosing.
James MO, Stacpoole PW. James MO, et al. Among authors: stacpoole pw. Pharmacogenomics. 2016 May;17(7):743-53. doi: 10.2217/pgs-2015-0012. Epub 2016 May 4. Pharmacogenomics. 2016. PMID: 27143230 Free PMC article. Review.
211 results