Weber IT - Search Results

1

Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.

Tie Y, Boross PI, Wang YF, Gaddis L, Liu F, Chen X, Tozser J, Harrison RW, Weber IT. Tie Y, et al. Among authors: weber it. FEBS J. 2005 Oct;272(20):5265-77. doi: 10.1111/j.1742-4658.2005.04923.x. FEBS J. 2005. PMID: 16218957 Free PMC article.

2

Kinetic and modeling studies of S3-S3' subsites of HIV proteinases.

Tözsér J, Weber IT, Gustchina A, Bláha I, Copeland TD, Louis JM, Oroszlan S. Tözsér J, et al. Among authors: weber it. Biochemistry. 1992 May 26;31(20):4793-800. doi: 10.1021/bi00135a008. Biochemistry. 1992. PMID: 1591240

3

Crystal structure at 1.5-A resolution of d(CGCICICG), an octanucleotide containing inosine, and its comparison with d(CGCG) and d(CGCGCG) structures.

Kumar VD, Harrison RW, Andrews LC, Weber IT. Kumar VD, et al. Among authors: weber it. Biochemistry. 1992 Feb 11;31(5):1541-50. doi: 10.1021/bi00120a035. Biochemistry. 1992. PMID: 1737011

4

Studies on the role of the S4 substrate binding site of HIV proteinases.

Tözsér J, Gustchina A, Weber IT, Blaha I, Wondrak EM, Oroszlan S. Tözsér J, et al. Among authors: weber it. FEBS Lett. 1991 Feb 25;279(2):356-60. doi: 10.1016/0014-5793(91)80186-7. FEBS Lett. 1991. PMID: 2001747 Free article.

5

Comparison of inhibitor binding in HIV-1 protease and in non-viral aspartic proteases: the role of the flap.

Gustchina A, Weber IT. Gustchina A, et al. Among authors: weber it. FEBS Lett. 1990 Aug 20;269(1):269-72. doi: 10.1016/0014-5793(90)81171-j. FEBS Lett. 1990. PMID: 2201571 Free article.

6

Preliminary crystal structure of Acinetobacter glutaminasificans glutaminase-asparaginase.

Ammon HL, Weber IT, Wlodawer A, Harrison RW, Gilliland GL, Murphy KC, Sjölin L, Roberts J. Ammon HL, et al. Among authors: weber it. J Biol Chem. 1988 Jan 5;263(1):150-6. J Biol Chem. 1988. PMID: 3275637 Free article.

7

Molecular dynamics simulations of HIV-1 protease with peptide substrate.

Harrison RW, Weber IT. Harrison RW, et al. Among authors: weber it. Protein Eng. 1994 Nov;7(11):1353-63. doi: 10.1093/protein/7.11.1353. Protein Eng. 1994. PMID: 7700867

8

Human beta-cell glucokinase. Dual role of Ser-151 in catalysis and hexose affinity.

Xu LZ, Harrison RW, Weber IT, Pilkis SJ. Xu LZ, et al. Among authors: weber it. J Biol Chem. 1995 Apr 28;270(17):9939-46. doi: 10.1074/jbc.270.17.9939. J Biol Chem. 1995. PMID: 7730377 Free article.

9

Sugar specificity of human beta-cell glucokinase: correlation of molecular models with kinetic measurements.

Xu LZ, Weber IT, Harrison RW, Gidh-Jain M, Pilkis SJ. Xu LZ, et al. Among authors: weber it. Biochemistry. 1995 May 9;34(18):6083-92. doi: 10.1021/bi00018a011. Biochemistry. 1995. PMID: 7742312

10

Site-directed mutagenesis studies on the determinants of sugar specificity and cooperative behavior of human beta-cell glucokinase.

Xu LZ, Zhang W, Weber IT, Harrison RW, Pilkis SJ. Xu LZ, et al. Among authors: weber it. J Biol Chem. 1994 Nov 4;269(44):27458-65. J Biol Chem. 1994. PMID: 7961659 Free article.

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