McMullen JR - Search Results

1

Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy.

Luo J, McMullen JR, Sobkiw CL, Zhang L, Dorfman AL, Sherwood MC, Logsdon MN, Horner JW, DePinho RA, Izumo S, Cantley LC. Luo J, et al. Among authors: mcmullen jr. Mol Cell Biol. 2005 Nov;25(21):9491-502. doi: 10.1128/MCB.25.21.9491-9502.2005. Mol Cell Biol. 2005. PMID: 16227599 Free PMC article.

2

Akt/protein kinase B promotes organ growth in transgenic mice.

Shioi T, McMullen JR, Kang PM, Douglas PS, Obata T, Franke TF, Cantley LC, Izumo S. Shioi T, et al. Among authors: mcmullen jr. Mol Cell Biol. 2002 Apr;22(8):2799-809. doi: 10.1128/MCB.22.8.2799-2809.2002. Mol Cell Biol. 2002. PMID: 11909972 Free PMC article.

3

Rapamycin attenuates load-induced cardiac hypertrophy in mice.

Shioi T, McMullen JR, Tarnavski O, Converso K, Sherwood MC, Manning WJ, Izumo S. Shioi T, et al. Among authors: mcmullen jr. Circulation. 2003 Apr 1;107(12):1664-70. doi: 10.1161/01.CIR.0000057979.36322.88. Epub 2003 Mar 17. Circulation. 2003. PMID: 12668503

4

Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy.

McMullen JR, Shioi T, Zhang L, Tarnavski O, Sherwood MC, Kang PM, Izumo S. McMullen JR, et al. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12355-60. doi: 10.1073/pnas.1934654100. Epub 2003 Sep 24. Proc Natl Acad Sci U S A. 2003. PMID: 14507992 Free PMC article.

5

The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway.

McMullen JR, Shioi T, Huang WY, Zhang L, Tarnavski O, Bisping E, Schinke M, Kong S, Sherwood MC, Brown J, Riggi L, Kang PM, Izumo S. McMullen JR, et al. J Biol Chem. 2004 Feb 6;279(6):4782-93. doi: 10.1074/jbc.M310405200. Epub 2003 Nov 3. J Biol Chem. 2004. PMID: 14597618 Free article.

6

Mouse cardiac surgery: comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies.

Tarnavski O, McMullen JR, Schinke M, Nie Q, Kong S, Izumo S. Tarnavski O, et al. Among authors: mcmullen jr. Physiol Genomics. 2004 Feb 13;16(3):349-60. doi: 10.1152/physiolgenomics.00041.2003. Physiol Genomics. 2004. PMID: 14679301

7

Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload.

McMullen JR, Sherwood MC, Tarnavski O, Zhang L, Dorfman AL, Shioi T, Izumo S. McMullen JR, et al. Circulation. 2004 Jun 22;109(24):3050-5. doi: 10.1161/01.CIR.0000130641.08705.45. Epub 2004 Jun 7. Circulation. 2004. PMID: 15184287

8

Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy.

McMullen JR, Shioi T, Zhang L, Tarnavski O, Sherwood MC, Dorfman AL, Longnus S, Pende M, Martin KA, Blenis J, Thomas G, Izumo S. McMullen JR, et al. Mol Cell Biol. 2004 Jul;24(14):6231-40. doi: 10.1128/MCB.24.14.6231-6240.2004. Mol Cell Biol. 2004. PMID: 15226426 Free PMC article.

9

A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes.

Meikle L, McMullen JR, Sherwood MC, Lader AS, Walker V, Chan JA, Kwiatkowski DJ. Meikle L, et al. Among authors: mcmullen jr. Hum Mol Genet. 2005 Feb 1;14(3):429-35. doi: 10.1093/hmg/ddi039. Epub 2004 Dec 15. Hum Mol Genet. 2005. PMID: 15601645

10

Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo.

Ha T, Li Y, Gao X, McMullen JR, Shioi T, Izumo S, Kelley JL, Zhao A, Haddad GE, Williams DL, Browder IW, Kao RL, Li C. Ha T, et al. Among authors: mcmullen jr. Free Radic Biol Med. 2005 Dec 15;39(12):1570-80. doi: 10.1016/j.freeradbiomed.2005.08.002. Epub 2005 Aug 22. Free Radic Biol Med. 2005. PMID: 16298682

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