Hutton M - Search Results

1

Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies.

Rodriguez-Martin T, Garcia-Blanco MA, Mansfield SG, Grover AC, Hutton M, Yu Q, Zhou J, Anderton BH, Gallo JM. Rodriguez-Martin T, et al. Among authors: hutton m. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15659-64. doi: 10.1073/pnas.0503150102. Epub 2005 Oct 17. Proc Natl Acad Sci U S A. 2005. PMID: 16230627 Free PMC article.

2

Sites of phosphorylation in tau and factors affecting their regulation.

Anderton BH, Betts J, Blackstock WP, Brion JP, Chapman S, Connell J, Dayanandan R, Gallo JM, Gibb G, Hanger DP, Hutton M, Kardalinou E, Leroy K, Lovestone S, Mack T, Reynolds CH, Van Slegtenhorst M. Anderton BH, et al. Among authors: hutton m. Biochem Soc Symp. 2001;(67):73-80. doi: 10.1042/bss0670073. Biochem Soc Symp. 2001. PMID: 11447841

3

The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons.

Utton MA, Connell J, Asuni AA, van Slegtenhorst M, Hutton M, de Silva R, Lees AJ, Miller CC, Anderton BH. Utton MA, et al. Among authors: hutton m. J Neurosci. 2002 Aug 1;22(15):6394-400. doi: 10.1523/JNEUROSCI.22-15-06394.2002. J Neurosci. 2002. PMID: 12151518 Free PMC article.

4

Effects on splicing and protein function of three mutations in codon N296 of tau in vitro.

Grover A, DeTure M, Yen SH, Hutton M. Grover A, et al. Among authors: hutton m. Neurosci Lett. 2002 Apr 19;323(1):33-6. doi: 10.1016/s0304-3940(02)00124-6. Neurosci Lett. 2002. PMID: 11911984

5

Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3beta identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes.

Connell JW, Gibb GM, Betts JC, Blackstock WP, Gallo J, Lovestone S, Hutton M, Anderton BH. Connell JW, et al. Among authors: hutton m. FEBS Lett. 2001 Mar 23;493(1):40-4. doi: 10.1016/s0014-5793(01)02267-0. FEBS Lett. 2001. PMID: 11278002 Free article.

6

Tau proteins with frontotemporal dementia-17 mutations have both altered expression levels and phosphorylation profiles in differentiated neuroblastoma cells.

Mack TG, Dayanandan R, Van Slegtenhorst M, Whone A, Hutton M, Lovestone S, Anderton BH. Mack TG, et al. Among authors: hutton m. Neuroscience. 2001;108(4):701-12. doi: 10.1016/s0306-4522(01)00434-1. Neuroscience. 2001. PMID: 11738505

7

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation.

Dayanandan R, Van Slegtenhorst M, Mack TG, Ko L, Yen SH, Leroy K, Brion JP, Anderton BH, Hutton M, Lovestone S. Dayanandan R, et al. Among authors: hutton m. FEBS Lett. 1999 Mar 12;446(2-3):228-32. doi: 10.1016/s0014-5793(99)00222-7. FEBS Lett. 1999. PMID: 10100846 Free article.

8

5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10.

Grover A, Houlden H, Baker M, Adamson J, Lewis J, Prihar G, Pickering-Brown S, Duff K, Hutton M. Grover A, et al. Among authors: hutton m. J Biol Chem. 1999 May 21;274(21):15134-43. doi: 10.1074/jbc.274.21.15134. J Biol Chem. 1999. PMID: 10329720 Free article.

9

A novel tau mutation in exon 9 (1260V) causes a four-repeat tauopathy.

Grover A, England E, Baker M, Sahara N, Adamson J, Granger B, Houlden H, Passant U, Yen SH, DeTure M, Hutton M. Grover A, et al. Among authors: hutton m. Exp Neurol. 2003 Nov;184(1):131-40. doi: 10.1016/s0014-4886(03)00393-5. Exp Neurol. 2003. PMID: 14637086

10

Evidence for independent mechanisms and a multiple-hit model of tau assembly.

DeTure M, Granger B, Grover A, Hutton M, Yen SH. DeTure M, et al. Among authors: hutton m. Biochem Biophys Res Commun. 2006 Jan 20;339(3):858-64. doi: 10.1016/j.bbrc.2005.11.087. Epub 2005 Nov 28. Biochem Biophys Res Commun. 2006. PMID: 16325769

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