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No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARdelta and PPARgamma act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma.
McGreavey LE, Turner F, Smith G, Boylan K, Timothy Bishop D, Forman D, Roland Wolf C, Barrett JH; Colorectal Cancer Study Group. McGreavey LE, et al. Pharmacogenet Genomics. 2005 Oct;15(10):713-21. doi: 10.1097/01.fpc.0000174786.85238.63. Pharmacogenet Genomics. 2005. PMID: 16141797