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Nitric oxide, NOC-12, and S-nitrosoglutathione modulate the skeletal muscle calcium release channel/ryanodine receptor by different mechanisms. An allosteric function for O2 in S-nitrosylation of the channel.
Sun J, Xu L, Eu JP, Stamler JS, Meissner G. Sun J, et al. Among authors: xu l. J Biol Chem. 2003 Mar 7;278(10):8184-9. doi: 10.1074/jbc.M211940200. Epub 2002 Dec 30. J Biol Chem. 2003. PMID: 12509428 Free article.
Cys-3635 is oxidized by O(2) versus O(2) subserves an allosteric function (Eu, J. P., Sun, J. H., Xu, L., Stamler, J. S., and Meissner, G. (2000) Cell 102, 499-509). Here we report that the NO donors NOC-12 and S-nitrosoglutathione both activate RyR1 by release of N …
Cys-3635 is oxidized by O(2) versus O(2) subserves an allosteric function (Eu, J. P., Sun, J. H., Xu, L., Stamler, J. S., and …
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