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309 results

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A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats.
Hummel CW, Geiser AG, Bryant HU, Cohen IR, Dally RD, Fong KC, Frank SA, Hinklin R, Jones SA, Lewis G, McCann DJ, Rudmann DG, Shepherd TA, Tian H, Wallace OB, Wang M, Wang Y, Dodge JA. Hummel CW, et al. Among authors: geiser ag. J Med Chem. 2005 Nov 3;48(22):6772-5. doi: 10.1021/jm050723z. J Med Chem. 2005. PMID: 16250633
Structure-activity relationships of SERMs optimized for uterine antagonism and ovarian safety.
Richardson TI, Frank SA, Wang M, Clarke CA, Jones SA, Ying BP, Kohlman DT, Wallace OB, Shepherd TA, Dally RD, Palkowitz AD, Geiser AG, Bryant HU, Henck JW, Cohen IR, Rudmann DG, McCann DJ, Coutant DE, Oldham SW, Hummel CW, Fong KC, Hinklin R, Lewis G, Tian H, Dodge JA. Richardson TI, et al. Among authors: geiser ag. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3544-9. doi: 10.1016/j.bmcl.2007.04.044. Epub 2007 Apr 24. Bioorg Med Chem Lett. 2007. PMID: 17482463
Benzothiophene and naphthalene derived constrained SERMs.
Wallace OB, Bryant HU, Shetler PK, Adrian MD, Geiser AG. Wallace OB, et al. Among authors: geiser ag. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5103-6. doi: 10.1016/j.bmcl.2004.07.072. Bioorg Med Chem Lett. 2004. PMID: 15380208
A selective estrogen receptor modulator for the treatment of hot flushes.
Wallace OB, Lauwers KS, Dodge JA, May SA, Calvin JR, Hinklin R, Bryant HU, Shetler PK, Adrian MD, Geiser AG, Sato M, Burris TP. Wallace OB, et al. Among authors: geiser ag. J Med Chem. 2006 Feb 9;49(3):843-6. doi: 10.1021/jm0509795. J Med Chem. 2006. PMID: 16451049
Novel 3-aryl indoles as progesterone receptor antagonists for uterine fibroids.
Richardson TI, Clarke CA, Yu KL, Yee YK, Bleisch TJ, Lopez JE, Jones SA, Hughes NE, Muehl BS, Lugar CW, Moore TL, Shetler PK, Zink RW, Osborne JJ, Montrose-Rafizadeh C, Patel N, Geiser AG, Galvin RJ, Dodge JA. Richardson TI, et al. Among authors: geiser ag. ACS Med Chem Lett. 2010 Dec 9;2(2):148-53. doi: 10.1021/ml100220b. eCollection 2011 Feb 10. ACS Med Chem Lett. 2010. PMID: 24900294 Free PMC article.
Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus.
Helvering LM, Adrian MD, Geiser AG, Estrem ST, Wei T, Huang S, Chen P, Dow ER, Calley JN, Dodge JA, Grese TA, Jones SA, Halladay DL, Miles RR, Onyia JE, Ma YL, Sato M, Bryant HU. Helvering LM, et al. Among authors: geiser ag. Biol Reprod. 2005 Apr;72(4):830-41. doi: 10.1095/biolreprod.104.034595. Epub 2004 Dec 1. Biol Reprod. 2005. PMID: 15576828
PINP: a serum biomarker of bone formation in the rat.
Hale LV, Galvin RJ, Risteli J, Ma YL, Harvey AK, Yang X, Cain RL, Zeng Q, Frolik CA, Sato M, Schmidt AL, Geiser AG. Hale LV, et al. Among authors: geiser ag. Bone. 2007 Apr;40(4):1103-9. doi: 10.1016/j.bone.2006.11.027. Epub 2006 Dec 22. Bone. 2007. PMID: 17258520
309 results