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Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.
Vandenbroucke RE, Dejonckheere E, Van Lint P, Demeestere D, Van Wonterghem E, Vanlaere I, Puimège L, Van Hauwermeiren F, De Rycke R, Mc Guire C, Campestre C, López-Otin C, Matthys P, Leclercq G, Libert C. Vandenbroucke RE, et al. J Neurosci. 2012 Jul 18;32(29):9805-16. doi: 10.1523/JNEUROSCI.0967-12.2012. J Neurosci. 2012. PMID: 22815495 Free PMC article.
Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
Gutiérrez-Fernández A, Inada M, Balbín M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noël A, Werb Z, Krane SM, López-Otín C, Puente XS. Gutiérrez-Fernández A, et al. FASEB J. 2007 Aug;21(10):2580-91. doi: 10.1096/fj.06-7860com. Epub 2007 Mar 28. FASEB J. 2007. PMID: 17392479 Free PMC article.
Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases.
Chabottaux V, Sounni NE, Pennington CJ, English WR, van den Brûle F, Blacher S, Gilles C, Munaut C, Maquoi E, Lopez-Otin C, Murphy G, Edwards DR, Foidart JM, Noël A. Chabottaux V, et al. Cancer Res. 2006 May 15;66(10):5165-72. doi: 10.1158/0008-5472.CAN-05-3012. Cancer Res. 2006. PMID: 16707440 Free article.
549 results