Clarke D - Search Results

1

Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes.

Griffin S, Clarke D, McCormick C, Rowlands D, Harris M. Griffin S, et al. Among authors: clarke d. J Virol. 2005 Dec;79(24):15525-36. doi: 10.1128/JVI.79.24.15525-15536.2005. J Virol. 2005. PMID: 16306623 Free PMC article.

2

Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro.

Clarke D, Griffin S, Beales L, Gelais CS, Burgess S, Harris M, Rowlands D. Clarke D, et al. J Biol Chem. 2006 Dec 1;281(48):37057-68. doi: 10.1074/jbc.M602434200. Epub 2006 Oct 10. J Biol Chem. 2006. PMID: 17032656 Free PMC article.

3

The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine.

Griffin SD, Beales LP, Clarke DS, Worsfold O, Evans SD, Jaeger J, Harris MP, Rowlands DJ. Griffin SD, et al. Among authors: clarke ds. FEBS Lett. 2003 Jan 30;535(1-3):34-8. doi: 10.1016/s0014-5793(02)03851-6. FEBS Lett. 2003. PMID: 12560074 Free article.

4

A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria.

Griffin SDC, Harvey R, Clarke DS, Barclay WS, Harris M, Rowlands DJ. Griffin SDC, et al. Among authors: clarke ds. J Gen Virol. 2004 Feb;85(Pt 2):451-461. doi: 10.1099/vir.0.19634-0. J Gen Virol. 2004. PMID: 14769903

5

Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system.

StGelais C, Tuthill TJ, Clarke DS, Rowlands DJ, Harris M, Griffin S. StGelais C, et al. Antiviral Res. 2007 Oct;76(1):48-58. doi: 10.1016/j.antiviral.2007.05.001. Epub 2007 Jun 4. Antiviral Res. 2007. PMID: 17574688 Free PMC article.

6

Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release.

Foster TL, Thompson GS, Kalverda AP, Kankanala J, Bentham M, Wetherill LF, Thompson J, Barker AM, Clarke D, Noerenberg M, Pearson AR, Rowlands DJ, Homans SW, Harris M, Foster R, Griffin S. Foster TL, et al. Among authors: clarke d. Hepatology. 2014 Feb;59(2):408-22. doi: 10.1002/hep.26685. Epub 2013 Dec 24. Hepatology. 2014. PMID: 24022996 Free PMC article.

7

Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins.

Peyret H, Gehin A, Thuenemann EC, Blond D, El Turabi A, Beales L, Clarke D, Gilbert RJ, Fry EE, Stuart DI, Holmes K, Stonehouse NJ, Whelan M, Rosenberg W, Lomonossoff GP, Rowlands DJ. Peyret H, et al. Among authors: clarke d. PLoS One. 2015 Apr 1;10(4):e0120751. doi: 10.1371/journal.pone.0120751. eCollection 2015. PLoS One. 2015. PMID: 25830365 Free PMC article.

8

BT1549 coordinates the in vitro IL-10 inducing activity of Bacteroides thetaiotaomicron.

Engelhart MJ, Brock OD, Till JM, Glowacki RWP, Cantwell JW, Clarke DJ, Wesener DA, Ahern PP. Engelhart MJ, et al. Among authors: clarke dj. Microbiol Spectr. 2025 Jan 27:e0166924. doi: 10.1128/spectrum.01669-24. Online ahead of print. Microbiol Spectr. 2025. PMID: 39868786 Free article.

9

Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders.

Lee S, McAfee JC, Lee J, Gomez A, Ledford AT, Clarke D, Min H, Gerstein MB, Boyle AP, Sullivan PF, Beltran AS, Won H. Lee S, et al. Among authors: clarke d. Cell. 2025 Jan 20:S0092-8674(24)01435-1. doi: 10.1016/j.cell.2024.12.022. Online ahead of print. Cell. 2025. PMID: 39848247

10

Near-field-driven thermal phonon lasing.

Karwat P, Bello FD, Clarke DDA, Pasławski G, Hess O. Karwat P, et al. Among authors: clarke dda. Opt Lett. 2025 Jan 15;50(2):305-308. doi: 10.1364/OL.539572. Opt Lett. 2025. PMID: 39815496

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