Miller AB - Search Results

1

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma.

Chao EY, Collins JL, Gaillard S, Miller AB, Wang L, Orband-Miller LA, Nolte RT, McDonnell DP, Willson TM, Zuercher WJ. Chao EY, et al. Among authors: miller ab. Bioorg Med Chem Lett. 2006 Feb 15;16(4):821-4. doi: 10.1016/j.bmcl.2005.11.030. Epub 2005 Nov 22. Bioorg Med Chem Lett. 2006. PMID: 16307879

2

Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma.

Zuercher WJ, Gaillard S, Orband-Miller LA, Chao EY, Shearer BG, Jones DG, Miller AB, Collins JL, McDonnell DP, Willson TM. Zuercher WJ, et al. Among authors: miller ab. J Med Chem. 2005 May 5;48(9):3107-9. doi: 10.1021/jm050161j. J Med Chem. 2005. PMID: 15857113

3

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.

Wang L, Zuercher WJ, Consler TG, Lambert MH, Miller AB, Orband-Miller LA, McKee DD, Willson TM, Nolte RT. Wang L, et al. Among authors: miller ab. J Biol Chem. 2006 Dec 8;281(49):37773-81. doi: 10.1074/jbc.M608410200. Epub 2006 Sep 21. J Biol Chem. 2006. PMID: 16990259 Free article.

4

On the intractability of estrogen-related receptor alpha as a target for activation by small molecules.

Hyatt SM, Lockamy EL, Stein RA, McDonnell DP, Miller AB, Orband-Miller LA, Willson TM, Zuercher WJ. Hyatt SM, et al. Among authors: miller ab. J Med Chem. 2007 Dec 27;50(26):6722-4. doi: 10.1021/jm7012387. Epub 2007 Dec 4. J Med Chem. 2007. PMID: 18052088 Free PMC article.

5

Synthesis of 3-alkyl naphthalenes as novel estrogen receptor ligands.

Fang J, Akwabi-Ameyaw A, Britton JE, Katamreddy SR, Navas F 3rd, Miller AB, Williams SP, Gray DW, Orband-Miller LA, Shearin J, Heyer D. Fang J, et al. Among authors: miller ab. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5075-7. doi: 10.1016/j.bmcl.2008.07.121. Epub 2008 Aug 5. Bioorg Med Chem Lett. 2008. PMID: 18722117

6

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids.

Wisely GB, Miller AB, Davis RG, Thornquest AD Jr, Johnson R, Spitzer T, Sefler A, Shearer B, Moore JT, Miller AB, Willson TM, Williams SP. Wisely GB, et al. Among authors: miller ab. Structure. 2002 Sep;10(9):1225-34. doi: 10.1016/s0969-2126(02)00829-8. Structure. 2002. PMID: 12220494 Free article.

7

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.

Oberfield JL, Collins JL, Holmes CP, Goreham DM, Cooper JP, Cobb JE, Lenhard JM, Hull-Ryde EA, Mohr CP, Blanchard SG, Parks DJ, Moore LB, Lehmann JM, Plunket K, Miller AB, Milburn MV, Kliewer SA, Willson TM. Oberfield JL, et al. Among authors: miller ab. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6102-6. doi: 10.1073/pnas.96.11.6102. Proc Natl Acad Sci U S A. 1999. PMID: 10339548 Free PMC article.

8

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors.

Gampe RT Jr, Montana VG, Lambert MH, Miller AB, Bledsoe RK, Milburn MV, Kliewer SA, Willson TM, Xu HE. Gampe RT Jr, et al. Among authors: miller ab. Mol Cell. 2000 Mar;5(3):545-55. doi: 10.1016/s1097-2765(00)80448-7. Mol Cell. 2000. PMID: 10882139 Free article.

9

FXR agonist activity of conformationally constrained analogs of GW 4064.

Akwabi-Ameyaw A, Bass JY, Caldwell RD, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, McFadyen RB, Miller AB, Navas F 3rd, Parks DJ, Spearing PK, Todd D, Williams SP, Bruce Wisely G. Akwabi-Ameyaw A, et al. Among authors: miller ab. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4733-9. doi: 10.1016/j.bmcl.2009.06.062. Epub 2009 Jun 21. Bioorg Med Chem Lett. 2009. PMID: 19586769

10

Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.

Catalano JG, Deaton DN, Furfine ES, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Willard DH Jr, Wright LL. Catalano JG, et al. Among authors: miller lr, miller ab. Bioorg Med Chem Lett. 2004 Jan 5;14(1):275-8. doi: 10.1016/j.bmcl.2003.09.088. Bioorg Med Chem Lett. 2004. PMID: 14684342

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