Cantley LC - Search Results

1

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.

Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC. Shaw RJ, et al. Among authors: cantley lc. Science. 2005 Dec 9;310(5754):1642-6. doi: 10.1126/science.1120781. Epub 2005 Nov 24. Science. 2005. PMID: 16308421 Free PMC article.

2

Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation.

Parker D, Jhala US, Radhakrishnan I, Yaffe MB, Reyes C, Shulman AI, Cantley LC, Wright PE, Montminy M. Parker D, et al. Among authors: cantley lc. Mol Cell. 1998 Sep;2(3):353-9. doi: 10.1016/s1097-2765(00)80279-8. Mol Cell. 1998. PMID: 9774973 Free article.

3

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

Fruman DA, Snapper SB, Yballe CM, Davidson L, Yu JY, Alt FW, Cantley LC. Fruman DA, et al. Among authors: cantley lc. Science. 1999 Jan 15;283(5400):393-7. doi: 10.1126/science.283.5400.393. Science. 1999. PMID: 9888855

4

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

Aramburu J, Yaffe MB, López-Rodríguez C, Cantley LC, Hogan PG, Rao A. Aramburu J, et al. Among authors: cantley lc. Science. 1999 Sep 24;285(5436):2129-33. doi: 10.1126/science.285.5436.2129. Science. 1999. PMID: 10497131

5

Minimal activators that bind to the KIX domain of p300/CBP identified by phage display screening.

Frangioni JV, LaRiccia LM, Cantley LC, Montminy MR. Frangioni JV, et al. Among authors: cantley lc. Nat Biotechnol. 2000 Oct;18(10):1080-5. doi: 10.1038/80280. Nat Biotechnol. 2000. PMID: 11017047

6

Lipid research picks up speed on the slopes of Taos.

Field SJ, Lamia KA, Rameh LE, Cantley LC. Field SJ, et al. Among authors: cantley lc. Dev Cell. 2002 Apr;2(4):407-10. doi: 10.1016/s1534-5807(02)00150-8. Dev Cell. 2002. PMID: 11970891 Free article.

7

The phosphoinositide 3-kinase pathway.

Cantley LC. Cantley LC. Science. 2002 May 31;296(5573):1655-7. doi: 10.1126/science.296.5573.1655. Science. 2002. PMID: 12040186 Review.

8

Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates.

Elia AE, Cantley LC, Yaffe MB. Elia AE, et al. Among authors: cantley lc. Science. 2003 Feb 21;299(5610):1228-31. doi: 10.1126/science.1079079. Science. 2003. PMID: 12595692

9

The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.

Carricaburu V, Lamia KA, Lo E, Favereaux L, Payrastre B, Cantley LC, Rameh LE. Carricaburu V, et al. Among authors: cantley lc. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9867-72. doi: 10.1073/pnas.1734038100. Epub 2003 Aug 1. Proc Natl Acad Sci U S A. 2003. PMID: 12897244 Free PMC article.

10

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.

Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC. Shaw RJ, et al. Among authors: cantley lc. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3329-35. doi: 10.1073/pnas.0308061100. Epub 2004 Feb 25. Proc Natl Acad Sci U S A. 2004. PMID: 14985505 Free PMC article.

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