Khan S - Search Results

1

In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent.

Rudek MA, Zhao M, Smith NF, Robey RW, He P, Hallur G, Khan S, Hidalgo M, Jimeno A, Colevas AD, Messersmith WA, Wolff AC, Baker SD. Rudek MA, et al. Among authors: khan s. Clin Cancer Res. 2005 Dec 1;11(23):8503-11. doi: 10.1158/1078-0432.CCR-05-1037. Clin Cancer Res. 2005. PMID: 16322314 Clinical Trial.

2

Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer.

Jimeno A, Hallur G, Chan A, Zhang X, Cusatis G, Chan F, Shah P, Chen R, Hamel E, Garrett-Mayer E, Khan S, Hidalgo M. Jimeno A, et al. Among authors: khan s. Mol Cancer Ther. 2007 May;6(5):1509-16. doi: 10.1158/1535-7163.MCT-06-0592. Epub 2007 May 4. Mol Cancer Ther. 2007. PMID: 17483439

3

Synthesis and antitumor evaluation of benzoylphenylurea analogs.

Gurulingappa H, Amador ML, Zhao M, Rudek MA, Hidalgo M, Khan SR. Gurulingappa H, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2213-6. doi: 10.1016/j.bmcl.2004.02.019. Bioorg Med Chem Lett. 2004. PMID: 15081011

4

Benzoylphenylurea sulfur analogues with potent antitumor activity.

Hallur G, Jimeno A, Dalrymple S, Zhu T, Jung MK, Hidalgo M, Isaacs JT, Sukumar S, Hamel E, Khan SR. Hallur G, et al. Among authors: khan sr. J Med Chem. 2006 Apr 6;49(7):2357-60. doi: 10.1021/jm051261s. J Med Chem. 2006. PMID: 16570932

5

Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy.

Anchoori RK, Kortenhorst MS, Hidalgo M, Sarkar T, Hallur G, Bai R, Diest PJ, Hamel E, Khan SR. Anchoori RK, et al. J Med Chem. 2008 Oct 9;51(19):5953-7. doi: 10.1021/jm800203e. Epub 2008 Sep 9. J Med Chem. 2008. PMID: 18778046 Free PMC article.

6

Fenugreek: a naturally occurring edible spice as an anticancer agent.

Shabbeer S, Sobolewski M, Anchoori RK, Kachhap S, Hidalgo M, Jimeno A, Davidson N, Carducci MA, Khan SR. Shabbeer S, et al. Among authors: khan sr. Cancer Biol Ther. 2009 Feb;8(3):272-8. doi: 10.4161/cbt.8.3.7443. Epub 2009 Feb 18. Cancer Biol Ther. 2009. PMID: 19197146 Free PMC article.

7

Design, synthesis and biological evaluation of novel riccardiphenol analogs.

Kumar SK, Amador M, Hidalgo M, Bhat SV, Khan SR. Kumar SK, et al. Bioorg Med Chem. 2005 Apr 15;13(8):2873-80. doi: 10.1016/j.bmc.2005.02.010. Bioorg Med Chem. 2005. PMID: 15781397

8

A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.

Chenna V, Hu C, Pramanik D, Aftab BT, Karikari C, Campbell NR, Hong SM, Zhao M, Rudek MA, Khan SR, Rudin CM, Maitra A. Chenna V, et al. Mol Cancer Ther. 2012 Jan;11(1):165-73. doi: 10.1158/1535-7163.MCT-11-0341. Epub 2011 Oct 25. Mol Cancer Ther. 2012. PMID: 22027695 Free PMC article.

9

Rational design of novel antiandrogens for neutralizing androgen receptor function in hormone refractory prostate cancer.

Singh P, Hallur G, Anchoori RK, Bakare O, Kageyama Y, Khan SR, Isaacs JT. Singh P, et al. Prostate. 2008 Oct 1;68(14):1570-81. doi: 10.1002/pros.20821. Prostate. 2008. PMID: 18668523 Free PMC article.

10

In vivo activity of a PSA-activated doxorubicin prodrug against PSA-producing human prostate cancer xenografts.

Khan SR, Denmeade SR. Khan SR, et al. Prostate. 2000 Sep 15;45(1):80-3. doi: 10.1002/1097-0045(20000915)45:1<80::aid-pros10>3.0.co;2-q. Prostate. 2000. PMID: 10960846

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