Giblett S - Search Results

1

Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts.

Mercer K, Giblett S, Green S, Lloyd D, DaRocha Dias S, Plumb M, Marais R, Pritchard C. Mercer K, et al. Among authors: giblett s. Cancer Res. 2005 Dec 15;65(24):11493-500. doi: 10.1158/0008-5472.CAN-05-2211. Cancer Res. 2005. PMID: 16357158 Free PMC article.

2

Disruption of the talin gene arrests mouse development at the gastrulation stage.

Monkley SJ, Zhou XH, Kinston SJ, Giblett SM, Hemmings L, Priddle H, Brown JE, Pritchard CA, Critchley DR, Fässler R. Monkley SJ, et al. Among authors: giblett sm. Dev Dyn. 2000 Dec;219(4):560-74. doi: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1079>3.0.CO;2-Y. Dev Dyn. 2000. PMID: 11084655 Free article.

3

MEK kinase activity is not necessary for Raf-1 function.

Hüser M, Luckett J, Chiloeches A, Mercer K, Iwobi M, Giblett S, Sun XM, Brown J, Marais R, Pritchard C. Hüser M, et al. Among authors: giblett s. EMBO J. 2001 Apr 17;20(8):1940-51. doi: 10.1093/emboj/20.8.1940. EMBO J. 2001. PMID: 11296227 Free PMC article.

4

Expression of kinase suppressor of Ras in the normal adult and embryonic mouse.

Giblett SM, Lloyd DJ, Light Y, Marais R, Pritchard CA. Giblett SM, et al. Cell Growth Differ. 2002 Jul;13(7):307-13. Cell Growth Differ. 2002. PMID: 12133899

5

A-Raf and Raf-1 work together to influence transient ERK phosphorylation and Gl/S cell cycle progression.

Mercer K, Giblett S, Oakden A, Brown J, Marais R, Pritchard C. Mercer K, et al. Among authors: giblett s. Oncogene. 2005 Aug 4;24(33):5207-17. doi: 10.1038/sj.onc.1208707. Oncogene. 2005. PMID: 15856007

6

Mouse models for BRAF-induced cancers.

Pritchard C, Carragher L, Aldridge V, Giblett S, Jin H, Foster C, Andreadi C, Kamata T. Pritchard C, et al. Among authors: giblett s. Biochem Soc Trans. 2007 Nov;35(Pt 5):1329-33. doi: 10.1042/BST0351329. Biochem Soc Trans. 2007. PMID: 17956344 Free PMC article. Review.

7

CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.

Noble C, Mercer K, Hussain J, Carragher L, Giblett S, Hayward R, Patterson C, Marais R, Pritchard CA. Noble C, et al. Among authors: giblett s. Mol Cell. 2008 Sep 26;31(6):862-72. doi: 10.1016/j.molcel.2008.08.026. Mol Cell. 2008. PMID: 18922468 Free PMC article.

8

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a.

Carragher LA, Snell KR, Giblett SM, Aldridge VS, Patel B, Cook SJ, Winton DJ, Marais R, Pritchard CA. Carragher LA, et al. Among authors: giblett sm. EMBO Mol Med. 2010 Nov;2(11):458-71. doi: 10.1002/emmm.201000099. EMBO Mol Med. 2010. PMID: 20941790 Free PMC article.

9

BRAF inactivation drives aneuploidy by deregulating CRAF.

Kamata T, Hussain J, Giblett S, Hayward R, Marais R, Pritchard C. Kamata T, et al. Among authors: giblett s. Cancer Res. 2010 Nov 1;70(21):8475-86. doi: 10.1158/0008-5472.CAN-10-0603. Epub 2010 Oct 26. Cancer Res. 2010. PMID: 20978199 Free PMC article.

10

The intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway.

Andreadi C, Cheung LK, Giblett S, Patel B, Jin H, Mercer K, Kamata T, Lee P, Williams A, McMahon M, Marais R, Pritchard C. Andreadi C, et al. Among authors: giblett s. Genes Dev. 2012 Sep 1;26(17):1945-58. doi: 10.1101/gad.193458.112. Epub 2012 Aug 14. Genes Dev. 2012. PMID: 22892241 Free PMC article.

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