Pritchard C - Search Results

1

Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts.

Mercer K, Giblett S, Green S, Lloyd D, DaRocha Dias S, Plumb M, Marais R, Pritchard C. Mercer K, et al. Among authors: pritchard c. Cancer Res. 2005 Dec 15;65(24):11493-500. doi: 10.1158/0008-5472.CAN-05-2211. Cancer Res. 2005. PMID: 16357158 Free PMC article.

2

Expression of kinase suppressor of Ras in the normal adult and embryonic mouse.

Giblett SM, Lloyd DJ, Light Y, Marais R, Pritchard CA. Giblett SM, et al. Cell Growth Differ. 2002 Jul;13(7):307-13. Cell Growth Differ. 2002. PMID: 12133899

3

Raf proteins and cancer: B-Raf is identified as a mutational target.

Mercer KE, Pritchard CA. Mercer KE, et al. Biochim Biophys Acta. 2003 Jun 5;1653(1):25-40. doi: 10.1016/s0304-419x(03)00016-7. Biochim Biophys Acta. 2003. PMID: 12781369 Review.

4

ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf.

Mercer K, Chiloeches A, Hüser M, Kiernan M, Marais R, Pritchard C. Mercer K, et al. Among authors: pritchard c. Oncogene. 2002 Jan 17;21(3):347-55. doi: 10.1038/sj.onc.1205101. Oncogene. 2002. PMID: 11821947

5

A-Raf and Raf-1 work together to influence transient ERK phosphorylation and Gl/S cell cycle progression.

Mercer K, Giblett S, Oakden A, Brown J, Marais R, Pritchard C. Mercer K, et al. Among authors: pritchard c. Oncogene. 2005 Aug 4;24(33):5207-17. doi: 10.1038/sj.onc.1208707. Oncogene. 2005. PMID: 15856007

6

Oncogenic Braf induces melanocyte senescence and melanoma in mice.

Dhomen N, Reis-Filho JS, da Rocha Dias S, Hayward R, Savage K, Delmas V, Larue L, Pritchard C, Marais R. Dhomen N, et al. Among authors: pritchard c. Cancer Cell. 2009 Apr 7;15(4):294-303. doi: 10.1016/j.ccr.2009.02.022. Cancer Cell. 2009. PMID: 19345328 Free article.

7

BRAF inactivation drives aneuploidy by deregulating CRAF.

Kamata T, Hussain J, Giblett S, Hayward R, Marais R, Pritchard C. Kamata T, et al. Among authors: pritchard c. Cancer Res. 2010 Nov 1;70(21):8475-86. doi: 10.1158/0008-5472.CAN-10-0603. Epub 2010 Oct 26. Cancer Res. 2010. PMID: 20978199 Free PMC article.

8

The intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway.

Andreadi C, Cheung LK, Giblett S, Patel B, Jin H, Mercer K, Kamata T, Lee P, Williams A, McMahon M, Marais R, Pritchard C. Andreadi C, et al. Among authors: pritchard c. Genes Dev. 2012 Sep 1;26(17):1945-58. doi: 10.1101/gad.193458.112. Epub 2012 Aug 14. Genes Dev. 2012. PMID: 22892241 Free PMC article.

9

B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts.

Pritchard CA, Hayes L, Wojnowski L, Zimmer A, Marais RM, Norman JC. Pritchard CA, et al. Mol Cell Biol. 2004 Jul;24(13):5937-52. doi: 10.1128/MCB.24.13.5937-5952.2004. Mol Cell Biol. 2004. PMID: 15199148 Free PMC article.

10

CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.

Noble C, Mercer K, Hussain J, Carragher L, Giblett S, Hayward R, Patterson C, Marais R, Pritchard CA. Noble C, et al. Among authors: pritchard ca. Mol Cell. 2008 Sep 26;31(6):862-72. doi: 10.1016/j.molcel.2008.08.026. Mol Cell. 2008. PMID: 18922468 Free PMC article.

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