Osada H - Search Results

1

Reveromycin A inhibits osteolytic bone metastasis of small-cell lung cancer cells, SBC-5, through an antiosteoclastic activity.

Muguruma H, Yano S, Kakiuchi S, Uehara H, Kawatani M, Osada H, Sone S. Muguruma H, et al. Among authors: osada h. Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8822-8. doi: 10.1158/1078-0432.CCR-05-1335. Clin Cancer Res. 2005. PMID: 16361571

2

Chemical modification of reveromycin A and its biological activities.

Shimizu T, Usui T, Machida K, Furuya K, Osada H, Nakata T. Shimizu T, et al. Among authors: osada h. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3363-6. doi: 10.1016/s0960-894x(02)00782-5. Bioorg Med Chem Lett. 2002. PMID: 12419362

3

Transmembrane domain of Bcl-2 is required for inhibition of ceramide synthesis, but not cytochrome c release in the pathway of inostamycin-induced apoptosis.

Kawatani M, Uchi M, Simizu S, Osada H, Imoto M. Kawatani M, et al. Among authors: osada h. Exp Cell Res. 2003 May 15;286(1):57-66. doi: 10.1016/s0014-4827(03)00098-3. Exp Cell Res. 2003. PMID: 12729794

4

RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines.

Simizu S, Takagi S, Tamura Y, Osada H. Simizu S, et al. Among authors: osada h. Cancer Res. 2005 Aug 15;65(16):7455-61. doi: 10.1158/0008-5472.CAN-04-4446. Cancer Res. 2005. PMID: 16103099

5

Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts.

Woo JT, Kawatani M, Kato M, Shinki T, Yonezawa T, Kanoh N, Nakagawa H, Takami M, Lee KH, Stern PH, Nagai K, Osada H. Woo JT, et al. Among authors: osada h. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4729-34. doi: 10.1073/pnas.0505663103. Epub 2006 Mar 13. Proc Natl Acad Sci U S A. 2006. PMID: 16537392 Free PMC article.

6

Iejimalides show anti-osteoclast activity via V-ATPase inhibition.

Kazami S, Muroi M, Kawatani M, Kubota T, Usui T, Kobayashi J, Osada H. Kazami S, et al. Among authors: osada h. Biosci Biotechnol Biochem. 2006 Jun;70(6):1364-70. doi: 10.1271/bbb.50644. Biosci Biotechnol Biochem. 2006. PMID: 16794315 Free article.

7

Photo-cross-linked small-molecule microarrays as chemical genomic tools for dissecting protein-ligand interactions.

Kanoh N, Asami A, Kawatani M, Honda K, Kumashiro S, Takayama H, Simizu S, Amemiya T, Kondoh Y, Hatakeyama S, Tsuganezawa K, Utata R, Tanaka A, Yokoyama S, Tashiro H, Osada H. Kanoh N, et al. Among authors: osada h. Chem Asian J. 2006 Dec 18;1(6):789-97. doi: 10.1002/asia.200600208. Chem Asian J. 2006. PMID: 17441122

8

Involvement of disulfide bond formation in the activation of heparanase.

Simizu S, Suzuki T, Muroi M, Lai NS, Takagi S, Dohmae N, Osada H. Simizu S, et al. Among authors: osada h. Cancer Res. 2007 Aug 15;67(16):7841-9. doi: 10.1158/0008-5472.CAN-07-1053. Cancer Res. 2007. PMID: 17699790

9

Epoxyquinol B shows antiangiogenic and antitumor effects by inhibiting VEGFR2, EGFR, FGFR, and PDGFR.

Kamiyama H, Kakeya H, Usui T, Nishikawa K, Shoji M, Hayashi Y, Osada H. Kamiyama H, et al. Among authors: osada h. Oncol Res. 2008;17(1):11-21. doi: 10.3727/096504008784046063. Oncol Res. 2008. PMID: 18488711

10

Synthesis and biological activities of reveromycin A and spirofungin A derivatives.

Shimizu T, Usui T, Fujikura M, Kawatani M, Satoh T, Machida K, Kanoh N, Woo JT, Osada H, Sodeoka M. Shimizu T, et al. Among authors: osada h. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3756-60. doi: 10.1016/j.bmcl.2008.05.054. Epub 2008 May 17. Bioorg Med Chem Lett. 2008. PMID: 18519164

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