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Both the hydrophobicity and a positively charged region flanking the C-terminal region of the transmembrane domain of signal-anchored proteins play critical roles in determining their targeting specificity to the endoplasmic reticulum or endosymbiotic organelles in Arabidopsis cells.
Lee J, Lee H, Kim J, Lee S, Kim DH, Kim S, Hwang I. Lee J, et al. Among authors: kim dh, kim s, kim j. Plant Cell. 2011 Apr;23(4):1588-607. doi: 10.1105/tpc.110.082230. Epub 2011 Apr 22. Plant Cell. 2011. PMID: 21515817 Free PMC article.
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