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Aldehyde dehydrogenase inhibitors: alpha,beta-acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture.
Quash G, Fournet G, Courvoisier C, Martinez RM, Chantepie J, Paret MJ, Pharaboz J, Joly-Pharaboz MO, Goré J, André J, Reichert U. Quash G, et al. Eur J Med Chem. 2008 May;43(5):906-16. doi: 10.1016/j.ejmech.2007.06.004. Epub 2007 Jul 6. Eur J Med Chem. 2008. PMID: 17692435
Synergetic bitherapy in mice with xenografts of human prostate cancer using a methional mimic (METLICO) and an aldehyde dehydrogenase 3 inhibitor (MATE): systemic intraperitoneal (IP) and targeted intra-tumoral (IT) administration.
Hiltbrand E, Fournet G, Giliberto JP, Paret MJ, Chantepie J, Morel D, Goré J, Reichert U, Mehier H, Rochedix ME, Quash G. Hiltbrand E, et al. Among authors: quash g. Curr Med Chem. 2009;16(10):1184-91. doi: 10.2174/092986709787846596. Curr Med Chem. 2009. PMID: 19355878
96 results