Linden AM - Search Results

1

The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.

Linden AM, Aller MI, Leppä E, Vekovischeva O, Aitta-Aho T, Veale EL, Mathie A, Rosenberg P, Wisden W, Korpi ER. Linden AM, et al. J Pharmacol Exp Ther. 2006 May;317(2):615-26. doi: 10.1124/jpet.105.098525. Epub 2006 Jan 5. J Pharmacol Exp Ther. 2006. PMID: 16397088

2

Uncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors alter the mRNA expression of proteins associated with the NMDA receptor complex.

Lindén AM, Väsänen J, Storvik M, Lakso M, Korpi ER, Wong G, Castrén E. Lindén AM, et al. Pharmacol Toxicol. 2001 Feb;88(2):98-105. doi: 10.1034/j.1600-0773.2001.d01-89.x. Pharmacol Toxicol. 2001. PMID: 11169168

3

Selective reduction of gamma-aminobutyric acid type A receptor delta subunit mRNA levels by MK-801 in rat dentate gyrus.

Sinkkonen ST, Lindén AM, Korpi ER, Wong G. Sinkkonen ST, et al. Among authors: linden am. Neurosci Lett. 2004 Jul 1;364(2):106-9. doi: 10.1016/j.neulet.2004.04.022. Neurosci Lett. 2004. PMID: 15196688

4

Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons.

Aller MI, Veale EL, Linden AM, Sandu C, Schwaninger M, Evans LJ, Korpi ER, Mathie A, Wisden W, Brickley SG. Aller MI, et al. Among authors: linden am. J Neurosci. 2005 Dec 7;25(49):11455-67. doi: 10.1523/JNEUROSCI.3153-05.2005. J Neurosci. 2005. PMID: 16339039 Free PMC article.

5

From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors.

Wulff P, Goetz T, Leppä E, Linden AM, Renzi M, Swinny JD, Vekovischeva OY, Sieghart W, Somogyi P, Korpi ER, Farrant M, Wisden W. Wulff P, et al. Among authors: linden am. Nat Neurosci. 2007 Jul;10(7):923-9. doi: 10.1038/nn1927. Epub 2007 Jun 17. Nat Neurosci. 2007. PMID: 17572671 Free PMC article.

6

Does ethanol act preferentially via selected brain GABAA receptor subtypes? the current evidence is ambiguous.

Korpi ER, Debus F, Linden AM, Malécot C, Leppä E, Vekovischeva O, Rabe H, Böhme I, Aller MI, Wisden W, Lüddens H. Korpi ER, et al. Among authors: linden am. Alcohol. 2007 May;41(3):163-76. doi: 10.1016/j.alcohol.2007.03.007. Alcohol. 2007. PMID: 17591542 Review.

7

TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics.

Linden AM, Sandu C, Aller MI, Vekovischeva OY, Rosenberg PH, Wisden W, Korpi ER. Linden AM, et al. J Pharmacol Exp Ther. 2007 Dec;323(3):924-34. doi: 10.1124/jpet.107.129544. Epub 2007 Sep 17. J Pharmacol Exp Ther. 2007. PMID: 17875609

8

Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors.

Saarelainen KS, Ranna M, Rabe H, Sinkkonen ST, Möykkynen T, Uusi-Oukari M, Linden AM, Lüddens H, Korpi ER. Saarelainen KS, et al. Among authors: linden am. J Neurochem. 2008 Apr;105(2):338-50. doi: 10.1111/j.1471-4159.2007.05136.x. Epub 2007 Nov 16. J Neurochem. 2008. PMID: 18021290 Free article.

9

K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands.

Linden AM, Aller MI, Leppä E, Rosenberg PH, Wisden W, Korpi ER. Linden AM, et al. J Pharmacol Exp Ther. 2008 Oct;327(1):277-86. doi: 10.1124/jpet.108.142083. Epub 2008 Jul 25. J Pharmacol Exp Ther. 2008. PMID: 18660435

10

Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites.

Chandra D, Halonen LM, Linden AM, Procaccini C, Hellsten K, Homanics GE, Korpi ER. Chandra D, et al. Among authors: linden am. Neuropsychopharmacology. 2010 Mar;35(4):999-1007. doi: 10.1038/npp.2009.203. Epub 2009 Dec 23. Neuropsychopharmacology. 2010. PMID: 20032968 Free PMC article.

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