Brown JM - Search Results

1

Coregulated human globin genes are frequently in spatial proximity when active.

Brown JM, Leach J, Reittie JE, Atzberger A, Lee-Prudhoe J, Wood WG, Higgs DR, Iborra FJ, Buckle VJ. Brown JM, et al. J Cell Biol. 2006 Jan 16;172(2):177-87. doi: 10.1083/jcb.200507073. J Cell Biol. 2006. PMID: 16418531 Free PMC article.

2

Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

Brown JM, Green J, das Neves RP, Wallace HA, Smith AJ, Hughes J, Gray N, Taylor S, Wood WG, Higgs DR, Iborra FJ, Buckle VJ. Brown JM, et al. J Cell Biol. 2008 Sep 22;182(6):1083-97. doi: 10.1083/jcb.200803174. J Cell Biol. 2008. PMID: 18809724 Free PMC article.

3

Detection of nascent RNA transcripts by fluorescence in situ hybridization.

Brown JM, Buckle VJ. Brown JM, et al. Methods Mol Biol. 2010;659:33-50. doi: 10.1007/978-1-60761-789-1_3. Methods Mol Biol. 2010. PMID: 20809302

4

Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts.

Renella R, Roberts NA, Brown JM, De Gobbi M, Bird LE, Hassanali T, Sharpe JA, Sloane-Stanley J, Ferguson DJ, Cordell J, Buckle VJ, Higgs DR, Wood WG. Renella R, et al. Among authors: brown jm. Blood. 2011 Jun 23;117(25):6928-38. doi: 10.1182/blood-2010-09-308478. Epub 2011 Mar 1. Blood. 2011. PMID: 21364188 Free article.

5

Intragenic enhancers act as alternative promoters.

Kowalczyk MS, Hughes JR, Garrick D, Lynch MD, Sharpe JA, Sloane-Stanley JA, McGowan SJ, De Gobbi M, Hosseini M, Vernimmen D, Brown JM, Gray NE, Collavin L, Gibbons RJ, Flint J, Taylor S, Buckle VJ, Milne TA, Wood WG, Higgs DR. Kowalczyk MS, et al. Among authors: brown jm. Mol Cell. 2012 Feb 24;45(4):447-58. doi: 10.1016/j.molcel.2011.12.021. Epub 2012 Jan 19. Mol Cell. 2012. PMID: 22264824 Free article.

6

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression.

Schödel J, Bardella C, Sciesielski LK, Brown JM, Pugh CW, Buckle V, Tomlinson IP, Ratcliffe PJ, Mole DR. Schödel J, et al. Among authors: brown jm. Nat Genet. 2012 Mar 11;44(4):420-5, S1-2. doi: 10.1038/ng.2204. Nat Genet. 2012. PMID: 22406644 Free PMC article.

7

Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I.

Babbs C, Roberts NA, Sanchez-Pulido L, McGowan SJ, Ahmed MR, Brown JM, Sabry MA; WGS500 Consortium; Bentley DR, McVean GA, Donnelly P, Gileadi O, Ponting CP, Higgs DR, Buckle VJ. Babbs C, et al. Among authors: brown jm. Haematologica. 2013 Sep;98(9):1383-7. doi: 10.3324/haematol.2013.089490. Epub 2013 May 28. Haematologica. 2013. PMID: 23716552 Free PMC article.

8

Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells.

Silva AM, Brown JM, Buckle VJ, Wade-Martins R, Lufino MM. Silva AM, et al. Among authors: brown jm. Hum Mol Genet. 2015 Jun 15;24(12):3457-71. doi: 10.1093/hmg/ddv096. Epub 2015 Mar 26. Hum Mol Genet. 2015. PMID: 25814655 Free PMC article.

9

Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models.

Brackley CA, Brown JM, Waithe D, Babbs C, Davies J, Hughes JR, Buckle VJ, Marenduzzo D. Brackley CA, et al. Among authors: brown jm. Genome Biol. 2016 Mar 31;17:59. doi: 10.1186/s13059-016-0909-0. Genome Biol. 2016. PMID: 27036497 Free PMC article.

10

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.

Brown JM, Roberts NA, Graham B, Waithe D, Lagerholm C, Telenius JM, De Ornellas S, Oudelaar AM, Scott C, Szczerbal I, Babbs C, Kassouf MT, Hughes JR, Higgs DR, Buckle VJ. Brown JM, et al. Nat Commun. 2018 Sep 21;9(1):3849. doi: 10.1038/s41467-018-06248-4. Nat Commun. 2018. PMID: 30242161 Free PMC article.

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