Higgs DR - Search Results

1

Coregulated human globin genes are frequently in spatial proximity when active.

Brown JM, Leach J, Reittie JE, Atzberger A, Lee-Prudhoe J, Wood WG, Higgs DR, Iborra FJ, Buckle VJ. Brown JM, et al. Among authors: higgs dr. J Cell Biol. 2006 Jan 16;172(2):177-87. doi: 10.1083/jcb.200507073. J Cell Biol. 2006. PMID: 16418531 Free PMC article.

2

Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype.

Anguita E, Sharpe JA, Sloane-Stanley JA, Tufarelli C, Higgs DR, Wood WG. Anguita E, et al. Among authors: higgs dr. Blood. 2002 Nov 15;100(10):3450-6. doi: 10.1182/blood-2002-05-1409. Epub 2002 Jul 5. Blood. 2002. PMID: 12393394 Free article.

3

De novo deletion within the telomeric region flanking the human alpha globin locus as a cause of alpha thalassaemia.

Viprakasit V, Kidd AM, Ayyub H, Horsley S, Hughes J, Higgs DR. Viprakasit V, et al. Among authors: higgs dr. Br J Haematol. 2003 Mar;120(5):867-75. doi: 10.1046/j.1365-2141.2003.04197.x. Br J Haematol. 2003. PMID: 12614224 Free article.

4

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease.

Tufarelli C, Stanley JA, Garrick D, Sharpe JA, Ayyub H, Wood WG, Higgs DR. Tufarelli C, et al. Among authors: higgs dr. Nat Genet. 2003 Jun;34(2):157-65. doi: 10.1038/ng1157. Nat Genet. 2003. PMID: 12730694

5

Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the alpha-thalassemia myelodysplasia syndrome (ATMDS).

Gibbons RJ, Pellagatti A, Garrick D, Wood WG, Malik N, Ayyub H, Langford C, Boultwood J, Wainscoat JS, Higgs DR. Gibbons RJ, et al. Among authors: higgs dr. Nat Genet. 2003 Aug;34(4):446-9. doi: 10.1038/ng1213. Nat Genet. 2003. PMID: 12858175

6

Deletion of the alpha-globin gene cluster as a cause of acquired alpha-thalassemia in myelodysplastic syndrome.

Steensma DP, Viprakasit V, Hendrick A, Goff DK, Leach J, Gibbons RJ, Higgs DR. Steensma DP, et al. Among authors: higgs dr. Blood. 2004 Feb 15;103(4):1518-20. doi: 10.1182/blood-2003-09-3222. Epub 2003 Oct 23. Blood. 2004. PMID: 14576055 Free article.

7

Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.

Anguita E, Hughes J, Heyworth C, Blobel GA, Wood WG, Higgs DR. Anguita E, et al. Among authors: higgs dr. EMBO J. 2004 Jul 21;23(14):2841-52. doi: 10.1038/sj.emboj.7600274. Epub 2004 Jun 24. EMBO J. 2004. PMID: 15215894 Free PMC article.

8

SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data.

Price TS, Regan R, Mott R, Hedman A, Honey B, Daniels RJ, Smith L, Greenfield A, Tiganescu A, Buckle V, Ventress N, Ayyub H, Salhan A, Pedraza-Diaz S, Broxholme J, Ragoussis J, Higgs DR, Flint J, Knight SJ. Price TS, et al. Among authors: higgs dr. Nucleic Acids Res. 2005 Jun 16;33(11):3455-64. doi: 10.1093/nar/gki643. Print 2005. Nucleic Acids Res. 2005. PMID: 15961730 Free PMC article.

9

How transcriptional and epigenetic programmes are played out on an individual mammalian gene cluster during lineage commitment and differentiation.

Higgs DR, Vernimmen D, De Gobbi M, Anguita E, Hughes J, Buckle V, Iborra F, Garrick D, Wood WG. Higgs DR, et al. Biochem Soc Symp. 2006;(73):11-22. doi: 10.1042/bss0730011. Biochem Soc Symp. 2006. PMID: 16626283 Free article.

10

A novel deletion causing alpha thalassemia clarifies the importance of the major human alpha globin regulatory element.

Viprakasit V, Harteveld CL, Ayyub H, Stanley JS, Giordano PC, Wood WG, Higgs DR. Viprakasit V, et al. Among authors: higgs dr. Blood. 2006 May 1;107(9):3811-2. doi: 10.1182/blood-2005-12-4834. Blood. 2006. PMID: 16627766 Free article. No abstract available.

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