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Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.
Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S Jr, Elmquist JK, Lowell BB. Dhillon H, et al. Among authors: cowley ma. Neuron. 2006 Jan 19;49(2):191-203. doi: 10.1016/j.neuron.2005.12.021. Neuron. 2006. PMID: 16423694 Free article.
Central serotonin and melanocortin pathways regulating energy homeostasis.
Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro J, Zigman JM, Cone RD, Elmquist JK. Heisler LK, et al. Among authors: cowley ma. Ann N Y Acad Sci. 2003 Jun;994:169-74. doi: 10.1111/j.1749-6632.2003.tb03177.x. Ann N Y Acad Sci. 2003. PMID: 12851313 Free article. Review.
Serotonin reciprocally regulates melanocortin neurons to modulate food intake.
Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, Mountjoy KG, Clifton PG, Lowell BB, Friedman JM, Horvath T, Butler AA, Elmquist JK, Cowley MA. Heisler LK, et al. Among authors: cowley ma. Neuron. 2006 Jul 20;51(2):239-49. doi: 10.1016/j.neuron.2006.06.004. Neuron. 2006. PMID: 16846858 Free article.
Activation of central melanocortin pathways by fenfluramine.
Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK. Heisler LK, et al. Among authors: cowley ma. Science. 2002 Jul 26;297(5581):609-11. doi: 10.1126/science.1072327. Science. 2002. PMID: 12142539
Leptin mediates the increase in blood pressure associated with obesity.
Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM, Bassi J, Elmquist JK, Keogh JM, Henning E, Myers MG Jr, Licinio J, Brown RD, Enriori PJ, O'Rahilly S, Sternson SM, Grove KL, Spanswick DC, Farooqi IS, Cowley MA. Simonds SE, et al. Among authors: cowley ma. Cell. 2014 Dec 4;159(6):1404-16. doi: 10.1016/j.cell.2014.10.058. Cell. 2014. PMID: 25480301 Free PMC article.
Hypothalamic POMC neurons promote cannabinoid-induced feeding.
Koch M, Varela L, Kim JG, Kim JD, Hernández-Nuño F, Simonds SE, Castorena CM, Vianna CR, Elmquist JK, Morozov YM, Rakic P, Bechmann I, Cowley MA, Szigeti-Buck K, Dietrich MO, Gao XB, Diano S, Horvath TL. Koch M, et al. Among authors: cowley ma. Nature. 2015 Mar 5;519(7541):45-50. doi: 10.1038/nature14260. Epub 2015 Feb 18. Nature. 2015. PMID: 25707796 Free PMC article.
138 results