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Topotecan is a substrate for multidrug resistance associated protein 4.
Tian Q, Zhang J, Chan SY, Tan TM, Duan W, Huang M, Zhu YZ, Chan E, Yu Q, Nie YQ, Ho PC, Li Q, Ng KY, Yang HY, Wei H, Bian JS, Zhou SF. Tian Q, et al. Among authors: duan w. Curr Drug Metab. 2006 Jan;7(1):105-18. doi: 10.2174/138920006774832550. Curr Drug Metab. 2006. PMID: 16454695
Small interfering RNA-mediated silencing of cytochrome P450 3A4 gene.
Chen J, Yang XX, Huang M, Hu ZP, He M, Duan W, Chan E, Sheu FS, Chen X, Zhou SF. Chen J, et al. Among authors: duan w. Drug Metab Dispos. 2006 Sep;34(9):1650-7. doi: 10.1124/dmd.106.009837. Epub 2006 Jun 7. Drug Metab Dispos. 2006. PMID: 16760227
St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis.
Hu ZP, Yang XX, Chan SY, Xu AL, Duan W, Zhu YZ, Sheu FS, Boelsterli UA, Chan E, Zhang Q, Wang JC, Ee PL, Koh HL, Huang M, Zhou SF. Hu ZP, et al. Among authors: duan w. Toxicol Appl Pharmacol. 2006 Oct 15;216(2):225-37. doi: 10.1016/j.taap.2006.05.020. Epub 2006 Jul 21. Toxicol Appl Pharmacol. 2006. PMID: 17015070
3,470 results