Crooks PA - Search Results

1

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release.

Zheng F, Bayram E, Sumithran SP, Ayers JT, Zhan CG, Schmitt JD, Dwoskin LP, Crooks PA. Zheng F, et al. Among authors: crooks pa. Bioorg Med Chem. 2006 May 1;14(9):3017-37. doi: 10.1016/j.bmc.2005.12.036. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431111

2

N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonist: inhibition of S(-)-nicotine-evoked [(3)H]dopamine overflow from superfused rat striatal slices.

Wilkins LH Jr, Haubner A, Ayers JT, Crooks PA, Dwoskin LP. Wilkins LH Jr, et al. Among authors: crooks pa. J Pharmacol Exp Ther. 2002 Jun;301(3):1088-96. doi: 10.1124/jpet.301.3.1088. J Pharmacol Exp Ther. 2002. PMID: 12023541

3

bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors.

Ayers JT, Dwoskin LP, Deaciuc AG, Grinevich VP, Zhu J, Crooks PA. Ayers JT, et al. Among authors: crooks pa. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3067-71. doi: 10.1016/s0960-894x(02)00687-x. Bioorg Med Chem Lett. 2002. PMID: 12372503

4

N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors.

Chen J, Norrholm S, Dwoskin LP, Crooks PA, Bai D. Chen J, et al. Among authors: crooks pa. Bioorg Med Chem Lett. 2003 Jan 6;13(1):97-100. doi: 10.1016/s0960-894x(02)00849-1. Bioorg Med Chem Lett. 2003. PMID: 12467625 Free PMC article.

5

N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors.

Wilkins LH Jr, Grinevich VP, Ayers JT, Crooks PA, Dwoskin LP. Wilkins LH Jr, et al. Among authors: crooks pa. J Pharmacol Exp Ther. 2003 Jan;304(1):400-10. doi: 10.1124/jpet.102.043349. J Pharmacol Exp Ther. 2003. PMID: 12490617

6

N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices.

Grinevich VP, Crooks PA, Sumithran SP, Haubner AJ, Ayers JT, Dwoskin LP. Grinevich VP, et al. Among authors: crooks pa. J Pharmacol Exp Ther. 2003 Sep;306(3):1011-20. doi: 10.1124/jpet.103.051789. Epub 2003 May 23. J Pharmacol Exp Ther. 2003. PMID: 12766255

7

Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.

Dwoskin LP, Sumithran SP, Zhu J, Deaciuc AG, Ayers JT, Crooks PA. Dwoskin LP, et al. Among authors: crooks pa. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1863-7. doi: 10.1016/j.bmcl.2003.10.073. Bioorg Med Chem Lett. 2004. PMID: 15050617

8

Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

Crooks PA, Ayers JT, Xu R, Sumithran SP, Grinevich VP, Wilkins LH, Deaciuc AG, Allen DD, Dwoskin LP. Crooks PA, et al. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1869-74. doi: 10.1016/j.bmcl.2003.10.074. Bioorg Med Chem Lett. 2004. PMID: 15050618

9

3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the blood-brain barrier choline transporter.

Geldenhuys WJ, Lockman PR, Nguyen TH, Van der Schyf CJ, Crooks PA, Dwoskin LP, Allen DD. Geldenhuys WJ, et al. Among authors: crooks pa. Bioorg Med Chem. 2005 Jul 1;13(13):4253-61. doi: 10.1016/j.bmc.2005.04.020. Bioorg Med Chem. 2005. PMID: 15878282

10

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2.

Zheng G, Dwoskin LP, Deaciuc AG, Zhu J, Jones MD, Crooks PA. Zheng G, et al. Among authors: crooks pa. Bioorg Med Chem. 2005 Jun 2;13(12):3899-909. doi: 10.1016/j.bmc.2005.04.013. Bioorg Med Chem. 2005. PMID: 15911306 Free PMC article.

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