Steinhilber D - Search Results

1

Synthesis of thieno[2,3-b]pyridinones acting as cytoprotectants and as inhibitors of [3H]glycine binding to the N-methyl-D-aspartate (NMDA) receptor.

Buchstaller HP, Siebert CD, Steinmetz R, Frank I, Berger ML, Gottschlich R, Leibrock J, Krug M, Steinhilber D, Noe CR. Buchstaller HP, et al. Among authors: steinhilber d. J Med Chem. 2006 Feb 9;49(3):864-71. doi: 10.1021/jm0503493. J Med Chem. 2006. PMID: 16451052

2

5-Lipoxygenase: a target for antiinflammatory drugs revisited.

Steinhilber D. Steinhilber D. Curr Med Chem. 1999 Jan;6(1):71-85. Curr Med Chem. 1999. PMID: 9873115 Review.

3

A simple cell line based in vitro test system for N-methyl-D-aspartate (NMDA) receptor ligands.

Steinmetz RD, Fava E, Nicotera P, Steinhilber D. Steinmetz RD, et al. Among authors: steinhilber d. J Neurosci Methods. 2002 Jan 15;113(1):99-110. doi: 10.1016/s0165-0270(01)00482-4. J Neurosci Methods. 2002. PMID: 11741727

4

Inhibition of the functional expression of N-methyl-D-aspartate receptors in a stably transformed cell line by cyclosporin A.

Steinmetz RD, Firla B, Steinhilber D. Steinmetz RD, et al. Among authors: steinhilber d. Biochem Pharmacol. 2004 Aug 1;68(3):563-71. doi: 10.1016/j.bcp.2004.04.017. Biochem Pharmacol. 2004. PMID: 15242822

5

Extraction and visualization of potential pharmacophore points using support vector machines: application to ligand-based virtual screening for COX-2 inhibitors.

Franke L, Byvatov E, Werz O, Steinhilber D, Schneider P, Schneider G. Franke L, et al. Among authors: steinhilber d. J Med Chem. 2005 Nov 3;48(22):6997-7004. doi: 10.1021/jm050619h. J Med Chem. 2005. PMID: 16250658

6

Design and synthesis of novel 2-amino-5-hydroxyindole derivatives that inhibit human 5-lipoxygenase.

Landwehr J, George S, Karg EM, Poeckel D, Steinhilber D, Troschuetz R, Werz O. Landwehr J, et al. Among authors: steinhilber d. J Med Chem. 2006 Jul 13;49(14):4327-32. doi: 10.1021/jm050801i. J Med Chem. 2006. PMID: 16821792

7

Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.

Franke L, Schwarz O, Müller-Kuhrt L, Hoernig C, Fischer L, George S, Tanrikulu Y, Schneider P, Werz O, Steinhilber D, Schneider G. Franke L, et al. Among authors: steinhilber d. J Med Chem. 2007 May 31;50(11):2640-6. doi: 10.1021/jm060655w. Epub 2007 Apr 27. J Med Chem. 2007. PMID: 17461565

8

Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid.

Werz O, Greiner C, Koeberle A, Hoernig C, George S, Popescu L, Syha I, Schubert-Zsilavecz M, Steinhilber D. Werz O, et al. Among authors: steinhilber d. J Med Chem. 2008 Sep 11;51(17):5449-53. doi: 10.1021/jm800588x. Epub 2008 Aug 19. J Med Chem. 2008. PMID: 18710209

9

A class of 5-benzylidene-2-phenylthiazolinones with high potency as direct 5-lipoxygenase inhibitors.

Hofmann B, Barzen S, Rödl CB, Kiehl A, Borig J, Zivković A, Stark H, Schneider G, Steinhilber D. Hofmann B, et al. Among authors: steinhilber d. J Med Chem. 2011 Mar 24;54(6):1943-7. doi: 10.1021/jm101165z. Epub 2011 Feb 22. J Med Chem. 2011. PMID: 21341744

10

SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase.

Hieke M, Rödl CB, Wisniewska JM, la Buscató E, Stark H, Schubert-Zsilavecz M, Steinhilber D, Hofmann B, Proschak E. Hieke M, et al. Among authors: steinhilber d. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1969-75. doi: 10.1016/j.bmcl.2012.01.038. Epub 2012 Jan 24. Bioorg Med Chem Lett. 2012. PMID: 22326163

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