Goldberg AL - Search Results

1

Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate.

Kisselev AF, Callard A, Goldberg AL. Kisselev AF, et al. Among authors: goldberg al. J Biol Chem. 2006 Mar 31;281(13):8582-90. doi: 10.1074/jbc.M509043200. Epub 2006 Feb 2. J Biol Chem. 2006. PMID: 16455650 Free article.

2

Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings.

Kisselev AF, Kaganovich D, Goldberg AL. Kisselev AF, et al. Among authors: goldberg al. J Biol Chem. 2002 Jun 21;277(25):22260-70. doi: 10.1074/jbc.M112360200. Epub 2002 Apr 1. J Biol Chem. 2002. PMID: 11927581 Free article.

3

The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.

Kisselev AF, Garcia-Calvo M, Overkleeft HS, Peterson E, Pennington MW, Ploegh HL, Thornberry NA, Goldberg AL. Kisselev AF, et al. Among authors: goldberg al. J Biol Chem. 2003 Sep 19;278(38):35869-77. doi: 10.1074/jbc.M303725200. Epub 2003 Jun 18. J Biol Chem. 2003. PMID: 12815064 Free article.

4

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

Kim HT, Kim KP, Lledias F, Kisselev AF, Scaglione KM, Skowyra D, Gygi SP, Goldberg AL. Kim HT, et al. Among authors: goldberg al. J Biol Chem. 2007 Jun 15;282(24):17375-86. doi: 10.1074/jbc.M609659200. Epub 2007 Apr 10. J Biol Chem. 2007. PMID: 17426036 Free article.

5

Inhibition of the Proteasome β2 Site Sensitizes Triple-Negative Breast Cancer Cells to β5 Inhibitors and Suppresses Nrf1 Activation.

Weyburne ES, Wilkins OM, Sha Z, Williams DA, Pletnev AA, de Bruin G, Overkleeft HS, Goldberg AL, Cole MD, Kisselev AF. Weyburne ES, et al. Among authors: goldberg al. Cell Chem Biol. 2017 Feb 16;24(2):218-230. doi: 10.1016/j.chembiol.2016.12.016. Epub 2017 Jan 26. Cell Chem Biol. 2017. PMID: 28132893 Free PMC article.

6

Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum.

Akopian TN, Kisselev AF, Goldberg AL. Akopian TN, et al. Among authors: goldberg al. J Biol Chem. 1997 Jan 17;272(3):1791-8. doi: 10.1074/jbc.272.3.1791. J Biol Chem. 1997. PMID: 8999862 Free article.

7

New insights into the mechanisms and importance of the proteasome in intracellular protein degradation.

Goldberg AL, Akopian TN, Kisselev AF, Lee DH, Rohrwild M. Goldberg AL, et al. Biol Chem. 1997 Mar-Apr;378(3-4):131-40. Biol Chem. 1997. PMID: 9165063 Review.

8

Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes.

Kisselev AF, Akopian TN, Goldberg AL. Kisselev AF, et al. Among authors: goldberg al. J Biol Chem. 1998 Jan 23;273(4):1982-9. doi: 10.1074/jbc.273.4.1982. J Biol Chem. 1998. PMID: 9442034 Free article.

9

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation.

Kisselev AF, Akopian TN, Woo KM, Goldberg AL. Kisselev AF, et al. Among authors: goldberg al. J Biol Chem. 1999 Feb 5;274(6):3363-71. doi: 10.1074/jbc.274.6.3363. J Biol Chem. 1999. PMID: 9920878 Free article.

10

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown.

Kisselev AF, Akopian TN, Castillo V, Goldberg AL. Kisselev AF, et al. Among authors: goldberg al. Mol Cell. 1999 Sep;4(3):395-402. doi: 10.1016/s1097-2765(00)80341-x. Mol Cell. 1999. PMID: 10518220 Free article.

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