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Page 1
Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.
Beevers RE, Buckley GM, Davies N, Fraser JL, Galvin FC, Hannah DR, Haughan AF, Jenkins K, Mack SR, Pitt WR, Ratcliffe AJ, Richard MD, Sabin V, Sharpe A, Williams SC. Beevers RE, et al. Among authors: hannah dr. Bioorg Med Chem Lett. 2006 May 1;16(9):2539-42. doi: 10.1016/j.bmcl.2006.01.090. Epub 2006 Feb 17. Bioorg Med Chem Lett. 2006. PMID: 16483773
Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.
Buckley GM, Davies N, Dyke HJ, Gilbert PJ, Hannah DR, Haughan AF, Hunt CA, Pitt WR, Profit RH, Ray NC, Richard MD, Sharpe A, Taylor AJ, Whitworth JM, Williams SC. Buckley GM, et al. Among authors: hannah dr. Bioorg Med Chem Lett. 2005 Feb 1;15(3):751-4. doi: 10.1016/j.bmcl.2004.11.015. Bioorg Med Chem Lett. 2005. PMID: 15664851
Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.
Birch HL, Buckley GM, Davies N, Dyke HJ, Frost EJ, Gilbert PJ, Hannah DR, Haughan AF, Madigan MJ, Morgan T, Pitt WR, Ratcliffe AJ, Ray NC, Richard MD, Sharpe A, Taylor AJ, Whitworth JM, Williams SC. Birch HL, et al. Among authors: hannah dr. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5335-9. doi: 10.1016/j.bmcl.2005.06.108. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16202581
Low molecular weight indole fragments as IMPDH inhibitors.
Beevers RE, Buckley GM, Davies N, Fraser JL, Galvin FC, Hannah DR, Haughan AF, Jenkins K, Mack SR, Pitt WR, Ratcliffe AJ, Richard MD, Sabin V, Sharpe A, Williams SC. Beevers RE, et al. Among authors: hannah dr. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. doi: 10.1016/j.bmcl.2006.01.089. Epub 2006 Feb 17. Bioorg Med Chem Lett. 2006. PMID: 16483769
7-Methoxybenzofuran-4-carboxamides as PDE 4 inhibitors: a potential treatment for asthma.
Buckley G, Cooper N, Dyke HJ, Galleway F, Gowers L, Gregory JC, Hannah DR, Haughan AF, Hellewell PG, Kendall HJ, Lowe C, Maxey R, Montana JG, Naylor R, Picken CL, Runcie KA, Sabin V, Tuladhar BR, Warneck JB. Buckley G, et al. Among authors: hannah dr. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2137-40. doi: 10.1016/s0960-894x(00)00426-1. Bioorg Med Chem Lett. 2000. PMID: 10999488
Synthesis and profile of SCH351591, a novel PDE4 inhibitor.
Billah M, Cooper N, Cuss F, Davenport RJ, Dyke HJ, Egan R, Ganguly A, Gowers L, Hannah DR, Haughan AF, Kendall HJ, Lowe C, Minnicozzi M, Montana JG, Naylor R, Oxford J, Peake JC, Piwinski JJ, Runcie KA, Sabin V, Sharpe A, Shih NY, Warneck JB. Billah M, et al. Among authors: hannah dr. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1621-3. doi: 10.1016/s0960-894x(02)00225-1. Bioorg Med Chem Lett. 2002. PMID: 12039576
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