Kong AN - Search Results

1

Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.

Hu R, Xu C, Shen G, Jain MR, Khor TO, Gopalkrishnan A, Lin W, Reddy B, Chan JY, Kong AN. Hu R, et al. Among authors: kong an. Cancer Lett. 2006 Nov 18;243(2):170-92. doi: 10.1016/j.canlet.2005.11.050. Epub 2006 Mar 3. Cancer Lett. 2006. PMID: 16516379

2

Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.

Xu C, Yuan X, Pan Z, Shen G, Kim JH, Yu S, Khor TO, Li W, Ma J, Kong AN. Xu C, et al. Among authors: kong an. Mol Cancer Ther. 2006 Aug;5(8):1918-26. doi: 10.1158/1535-7163.MCT-05-0497. Mol Cancer Ther. 2006. PMID: 16928811

3

Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice.

Khor TO, Hu R, Shen G, Jeong WS, Hebbar V, Chen C, Xu C, Nair S, Reddy B, Chada K, Kong AN. Khor TO, et al. Among authors: kong an. Biopharm Drug Dispos. 2006 Dec;27(9):407-20. doi: 10.1002/bdd.522. Biopharm Drug Dispos. 2006. PMID: 16952200

4

Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice.

Nair S, Xu C, Shen G, Hebbar V, Gopalakrishnan A, Hu R, Jain MR, Lin W, Keum YS, Liew C, Chan JY, Kong AN. Nair S, et al. Among authors: kong an. Pharm Res. 2006 Nov;23(11):2621-37. doi: 10.1007/s11095-006-9099-x. Epub 2006 Sep 13. Pharm Res. 2006. PMID: 16969697

5

In vivo pharmacokinetics, activation of MAPK signaling and induction of phase II/III drug metabolizing enzymes/transporters by cancer chemopreventive compound BHA in the mice.

Hu R, Shen G, Yerramilli UR, Lin W, Xu C, Nair S, Kong AN. Hu R, et al. Among authors: kong an. Arch Pharm Res. 2006 Oct;29(10):911-20. doi: 10.1007/BF02973914. Arch Pharm Res. 2006. PMID: 17121188

6

Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice.

Nair S, Xu C, Shen G, Hebbar V, Gopalakrishnan A, Hu R, Jain MR, Liew C, Chan JY, Kong AN. Nair S, et al. Among authors: kong an. Toxicol Lett. 2007 Jan 10;168(1):21-39. doi: 10.1016/j.toxlet.2006.10.012. Epub 2006 Nov 10. Toxicol Lett. 2007. PMID: 17127020 Free PMC article.

7

Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.

Shen G, Khor TO, Hu R, Yu S, Nair S, Ho CT, Reddy BS, Huang MT, Newmark HL, Kong AN. Shen G, et al. Among authors: kong an. Cancer Res. 2007 Oct 15;67(20):9937-44. doi: 10.1158/0008-5472.CAN-07-1112. Cancer Res. 2007. PMID: 17942926

8

Pharmacokinetics and pharmacodynamics of phase II drug metabolizing/antioxidant enzymes gene response by anticancer agent sulforaphane in rat lymphocytes.

Wang H, Khor TO, Yang Q, Huang Y, Wu TY, Saw CL, Lin W, Androulakis IP, Kong AN. Wang H, et al. Among authors: kong an. Mol Pharm. 2012 Oct 1;9(10):2819-27. doi: 10.1021/mp300130k. Epub 2012 Sep 11. Mol Pharm. 2012. PMID: 22931102 Free PMC article.

9

Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation.

Zhang C, Su ZY, Khor TO, Shu L, Kong AN. Zhang C, et al. Among authors: kong an. Biochem Pharmacol. 2013 May 1;85(9):1398-404. doi: 10.1016/j.bcp.2013.02.010. Epub 2013 Feb 14. Biochem Pharmacol. 2013. PMID: 23416117 Free PMC article.

10

Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane.

Su ZY, Zhang C, Lee JH, Shu L, Wu TY, Khor TO, Conney AH, Lu YP, Kong AN. Su ZY, et al. Among authors: kong an. Cancer Prev Res (Phila). 2014 Mar;7(3):319-29. doi: 10.1158/1940-6207.CAPR-13-0313-T. Epub 2014 Jan 17. Cancer Prev Res (Phila). 2014. PMID: 24441674

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