Hyman BT - Search Results

1

Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases.

Bodner RA, Outeiro TF, Altmann S, Maxwell MM, Cho SH, Hyman BT, McLean PJ, Young AB, Housman DE, Kazantsev AG. Bodner RA, et al. Among authors: hyman bt. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4246-51. doi: 10.1073/pnas.0511256103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537516 Free PMC article.

2

Localization of non-N-methyl-D-aspartate glutamate receptors in normal and Alzheimer hippocampal formation.

Hyman BT, Penney JB Jr, Blackstone CD, Young AB. Hyman BT, et al. Ann Neurol. 1994 Jan;35(1):31-7. doi: 10.1002/ana.410350106. Ann Neurol. 1994. PMID: 8285589

3

Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations.

McLean PJ, Kawamata H, Ribich S, Hyman BT. McLean PJ, et al. Among authors: hyman bt. J Biol Chem. 2000 Mar 24;275(12):8812-6. doi: 10.1074/jbc.275.12.8812. J Biol Chem. 2000. PMID: 10722726 Free article.

4

Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: hyman bt. J Neurochem. 2000 Aug;75(2):583-93. doi: 10.1046/j.1471-4159.2000.0750583.x. J Neurochem. 2000. PMID: 10899933 Free article.

5

Subcellular localization of alpha-synuclein in primary neuronal cultures: effect of missense mutations.

McLean PJ, Ribich S, Hyman BT. McLean PJ, et al. Among authors: hyman bt. J Neural Transm Suppl. 2000;(58):53-63. doi: 10.1007/978-3-7091-6284-2_5. J Neural Transm Suppl. 2000. PMID: 11128613

6

Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Weinmaster G, Selkoe DJ, Hyman BT. Berezovska O, et al. Among authors: hyman bt. Ann N Y Acad Sci. 2000;920:223-6. doi: 10.1111/j.1749-6632.2000.tb06926.x. Ann N Y Acad Sci. 2000. PMID: 11193154

7

Interaction of alpha-synuclein and synphilin-1: effect of Parkinson's disease-associated mutations.

Kawamata H, McLean PJ, Sharma N, Hyman BT. Kawamata H, et al. Among authors: hyman bt. J Neurochem. 2001 May;77(3):929-34. doi: 10.1046/j.1471-4159.2001.00301.x. J Neurochem. 2001. PMID: 11331421 Free article.

8

A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study.

Sharma N, Hewett J, Ozelius LJ, Ramesh V, McLean PJ, Breakefield XO, Hyman BT. Sharma N, et al. Among authors: hyman bt. Am J Pathol. 2001 Jul;159(1):339-44. doi: 10.1016/s0002-9440(10)61700-2. Am J Pathol. 2001. PMID: 11438481 Free PMC article.

9

Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.

McLean PJ, Kawamata H, Hyman BT. McLean PJ, et al. Among authors: hyman bt. Neuroscience. 2001;104(3):901-12. doi: 10.1016/s0306-4522(01)00113-0. Neuroscience. 2001. PMID: 11440819

10

Alpha-synuclein has an altered conformation and shows a tight intermolecular interaction with ubiquitin in Lewy bodies.

Sharma N, McLean PJ, Kawamata H, Irizarry MC, Hyman BT. Sharma N, et al. Among authors: hyman bt. Acta Neuropathol. 2001 Oct;102(4):329-34. doi: 10.1007/s004010100369. Acta Neuropathol. 2001. PMID: 11603807

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