Outeiro TF - Search Results

1

Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases.

Bodner RA, Outeiro TF, Altmann S, Maxwell MM, Cho SH, Hyman BT, McLean PJ, Young AB, Housman DE, Kazantsev AG. Bodner RA, et al. Among authors: outeiro tf. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4246-51. doi: 10.1073/pnas.0511256103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537516 Free PMC article.

2

Yeast as a drug discovery platform in Huntington's and Parkinson's diseases.

Outeiro TF, Giorgini F. Outeiro TF, et al. Biotechnol J. 2006 Mar;1(3):258-69. doi: 10.1002/biot.200500043. Biotechnol J. 2006. PMID: 16897706 Review.

3

Detection of novel intracellular alpha-synuclein oligomeric species by fluorescence lifetime imaging.

Klucken J, Outeiro TF, Nguyen P, McLean PJ, Hyman BT. Klucken J, et al. Among authors: outeiro tf. FASEB J. 2006 Oct;20(12):2050-7. doi: 10.1096/fj.05-5422com. FASEB J. 2006. PMID: 17012257

4

Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation.

Outeiro TF, Klucken J, Strathearn KE, Liu F, Nguyen P, Rochet JC, Hyman BT, McLean PJ. Outeiro TF, et al. Biochem Biophys Res Commun. 2006 Dec 22;351(3):631-8. doi: 10.1016/j.bbrc.2006.10.085. Epub 2006 Oct 26. Biochem Biophys Res Commun. 2006. PMID: 17081499 Free PMC article.

5

Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.

St Martin JL, Klucken J, Outeiro TF, Nguyen P, Keller-McGandy C, Cantuti-Castelvetri I, Grammatopoulos TN, Standaert DG, Hyman BT, McLean PJ. St Martin JL, et al. Among authors: outeiro tf. J Neurochem. 2007 Mar;100(6):1449-57. doi: 10.1111/j.1471-4159.2006.04310.x. Epub 2007 Jan 4. J Neurochem. 2007. PMID: 17241127 Free article.

6

Pharmacological inhibition of PARP-1 reduces alpha-synuclein- and MPP+-induced cytotoxicity in Parkinson's disease in vitro models.

Outeiro TF, Grammatopoulos TN, Altmann S, Amore A, Standaert DG, Hyman BT, Kazantsev AG. Outeiro TF, et al. Biochem Biophys Res Commun. 2007 Jun 8;357(3):596-602. doi: 10.1016/j.bbrc.2007.03.163. Epub 2007 Apr 5. Biochem Biophys Res Commun. 2007. PMID: 17449015

7

Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.

Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Outeiro TF, et al. Science. 2007 Jul 27;317(5837):516-9. doi: 10.1126/science.1143780. Epub 2007 Jun 21. Science. 2007. PMID: 17588900

8

Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro.

Grammatopoulos TN, Outeiro TF, Hyman BT, Standaert DG. Grammatopoulos TN, et al. Among authors: outeiro tf. Biochem Biophys Res Commun. 2007 Nov 23;363(3):846-51. doi: 10.1016/j.bbrc.2007.09.043. Epub 2007 Sep 21. Biochem Biophys Res Commun. 2007. PMID: 17900533 Free PMC article.

9

Therapeutic role of sirtuins in neurodegenerative disease.

Outeiro TF, Marques O, Kazantsev A. Outeiro TF, et al. Biochim Biophys Acta. 2008 Jun;1782(6):363-9. doi: 10.1016/j.bbadis.2008.02.010. Epub 2008 Mar 7. Biochim Biophys Acta. 2008. PMID: 18373985 Free article. Review.

10

Formation of toxic oligomeric alpha-synuclein species in living cells.

Outeiro TF, Putcha P, Tetzlaff JE, Spoelgen R, Koker M, Carvalho F, Hyman BT, McLean PJ. Outeiro TF, et al. PLoS One. 2008 Apr 2;3(4):e1867. doi: 10.1371/journal.pone.0001867. PLoS One. 2008. PMID: 18382657 Free PMC article.

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