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Particulate hexavalent chromium inhibits global transcription of genes in DNA repair pathways, particularly targeting homologous recombination repair, base excision repair, mismatch repair and microhomology-mediated end-joining.
Meaza I, Cahill CR, Speer RM, Kouokam JC, Wise JP Sr. Meaza I, et al. Among authors: kouokam jc. J Hazard Mater. 2024 Dec 15;485:136892. doi: 10.1016/j.jhazmat.2024.136892. Online ahead of print. J Hazard Mater. 2024. PMID: 39706010
Particulate hexavalent chromium exposure induces DNA double-strand breaks and inhibits homologous recombination repair in rat and human lung tissues.
Lu H, Wise SS, Toyoda JH, Speer RM, Croom-Perez TJ, Meaza I, Kouokam JC, Wise JL, Hoyle G, Chen N, Wise JP Jr, Kondo K, Toba H, Takizawa H, Wise JP Sr. Lu H, et al. Among authors: kouokam jc. Chemosphere. 2024 Dec 24;370:143982. doi: 10.1016/j.chemosphere.2024.143982. Online ahead of print. Chemosphere. 2024. PMID: 39701314
Chromium Selectively Accumulates in the Rat Hippocampus after 90 Days of Exposure to Cr(VI) in Drinking Water and Induces Age- and Sex-Dependent Metal Dyshomeostasis.
Vielee ST, Buchanan WJ, Roof SH, Kahloon R, Evans E, Isibor J, Patel M, Meaza I, Lu H, Williams AR, Kouokam JC, Wise SS, Guo L, Wise RM, Wise JL, Cai L, Cai J, Wise JP Jr. Vielee ST, et al. Among authors: kouokam jc. Toxics. 2024 Oct 3;12(10):722. doi: 10.3390/toxics12100722. Toxics. 2024. PMID: 39453142 Free PMC article.
Employing a Toxic Aging Coin approach to assess hexavalent chromium (Cr[VI])-induced neurotoxic effects on behavior: Heads for age differences.
Vielee ST, Isibor J, Buchanan WJ, Roof SH, Patel M, Meaza I, Williams A, Toyoda JH, Lu H, Wise SS, Kouokam JC, Young Wise J, Abouiessa AM, Cai J, Cai L, Wise JP Jr. Vielee ST, et al. Among authors: kouokam jc. Toxicol Appl Pharmacol. 2024 Aug;489:117007. doi: 10.1016/j.taap.2024.117007. Epub 2024 Jun 18. Toxicol Appl Pharmacol. 2024. PMID: 38901695
Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial epithelial cells.
Meaza I, Williams AR, Lu H, Kouokam JC, Toyoda JH, Croom-Perez TJ, Wise SS, Aboueissa AE, Wise JP Sr. Meaza I, et al. Among authors: kouokam jc. Toxicol Appl Pharmacol. 2023 Nov 15;479:116711. doi: 10.1016/j.taap.2023.116711. Epub 2023 Oct 5. Toxicol Appl Pharmacol. 2023. PMID: 37805091 Free PMC article.
Chromium distribution in an oropharyngeal aspiration model for hexavalent chromium in rats.
Wise SS, Lu H, Speer RM, Wise JP Jr, Young J, Toyoda JH, Meaza I, Croom-Perez TJ, Kouokam JC, Specht A, Liu KJ, Hoyle GW, Wise JP Sr. Wise SS, et al. Among authors: kouokam jc. Toxicol Appl Pharmacol. 2022 Dec 15;457:116294. doi: 10.1016/j.taap.2022.116294. Epub 2022 Oct 22. Toxicol Appl Pharmacol. 2022. PMID: 36283442 Free PMC article.
30 results