Zhuang ZY - Search Results

1

A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.

Zhuang ZY, Wen YR, Zhang DR, Borsello T, Bonny C, Strichartz GR, Decosterd I, Ji RR. Zhuang ZY, et al. J Neurosci. 2006 Mar 29;26(13):3551-60. doi: 10.1523/JNEUROSCI.5290-05.2006. J Neurosci. 2006. PMID: 16571763 Free PMC article.

2

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

Jin SX, Zhuang ZY, Woolf CJ, Ji RR. Jin SX, et al. Among authors: zhuang zy. J Neurosci. 2003 May 15;23(10):4017-22. doi: 10.1523/JNEUROSCI.23-10-04017.2003. J Neurosci. 2003. PMID: 12764087 Free PMC article.

3

Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.

Zhuang ZY, Xu H, Clapham DE, Ji RR. Zhuang ZY, et al. J Neurosci. 2004 Sep 22;24(38):8300-9. doi: 10.1523/JNEUROSCI.2893-04.2004. J Neurosci. 2004. PMID: 15385613 Free PMC article.

4

Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.

Kawasaki Y, Kohno T, Zhuang ZY, Brenner GJ, Wang H, Van Der Meer C, Befort K, Woolf CJ, Ji RR. Kawasaki Y, et al. Among authors: zhuang zy. J Neurosci. 2004 Sep 22;24(38):8310-21. doi: 10.1523/JNEUROSCI.2396-04.2004. J Neurosci. 2004. PMID: 15385614 Free PMC article.

5

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model.

Zhuang ZY, Gerner P, Woolf CJ, Ji RR. Zhuang ZY, et al. Pain. 2005 Mar;114(1-2):149-59. doi: 10.1016/j.pain.2004.12.022. Epub 2005 Jan 26. Pain. 2005. PMID: 15733640

6

Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine.

Zhuang ZY, Kawasaki Y, Tan PH, Wen YR, Huang J, Ji RR. Zhuang ZY, et al. Brain Behav Immun. 2007 Jul;21(5):642-51. doi: 10.1016/j.bbi.2006.11.003. Epub 2006 Dec 15. Brain Behav Immun. 2007. PMID: 17174525 Free PMC article.

7

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain.

Kawasaki Y, Xu ZZ, Wang X, Park JY, Zhuang ZY, Tan PH, Gao YJ, Roy K, Corfas G, Lo EH, Ji RR. Kawasaki Y, et al. Among authors: zhuang zy. Nat Med. 2008 Mar;14(3):331-6. doi: 10.1038/nm1723. Epub 2008 Feb 10. Nat Med. 2008. PMID: 18264108 Free PMC article.

8

Protein kinases as potential targets for the treatment of pathological pain.

Ji RR, Kawasaki Y, Zhuang ZY, Wen YR, Zhang YQ. Ji RR, et al. Among authors: zhuang zy. Handb Exp Pharmacol. 2007;(177):359-89. doi: 10.1007/978-3-540-33823-9_13. Handb Exp Pharmacol. 2007. PMID: 17087130 Review.

9

Possible role of spinal astrocytes in maintaining chronic pain sensitization: review of current evidence with focus on bFGF/JNK pathway.

Ji RR, Kawasaki Y, Zhuang ZY, Wen YR, Decosterd I. Ji RR, et al. Among authors: zhuang zy. Neuron Glia Biol. 2006 Nov;2(4):259-69. doi: 10.1017/S1740925X07000403. Neuron Glia Biol. 2006. PMID: 17710215 Free PMC article.

10

Doxepin by topical application and intrathecal route in rats.

Gerner P, Srinivasa V, Zizza AM, Zhuang ZY, Luo S, Zurakowski D, Eappen S, Wang G. Gerner P, et al. Among authors: zhuang zy. Anesth Analg. 2006 Jan;102(1):283-7. doi: 10.1213/01.ane.0000183639.37428.4d. Anesth Analg. 2006. PMID: 16368844

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