Khuri FR - Search Results

1

Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).

Yue P, Zhou Z, Khuri FR, Sun SY. Yue P, et al. Among authors: khuri fr. Cancer Biol Ther. 2006 May;5(5):492-7. doi: 10.4161/cbt.5.5.2565. Epub 2006 May 2. Cancer Biol Ther. 2006. PMID: 16582599 Free article.

2

p53 upregulates death receptor 4 expression through an intronic p53 binding site.

Liu X, Yue P, Khuri FR, Sun SY. Liu X, et al. Among authors: khuri fr. Cancer Res. 2004 Aug 1;64(15):5078-83. doi: 10.1158/0008-5472.CAN-04-1195. Cancer Res. 2004. PMID: 15289308

3

The farnesyltransferase inhibitor Lonafarnib induces growth arrest or apoptosis of human lung cancer cells without downregulation of Akt.

Sun SY, Zhou Z, Wang R, Fu H, Khuri FR. Sun SY, et al. Among authors: khuri fr. Cancer Biol Ther. 2004 Nov;3(11):1092-8; discussion 1099-1101. doi: 10.4161/cbt.3.11.1176. Epub 2004 Nov 12. Cancer Biol Ther. 2004. PMID: 15467440 Free article.

4

c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.

Zou W, Liu X, Yue P, Zhou Z, Sporn MB, Lotan R, Khuri FR, Sun SY. Zou W, et al. Among authors: khuri fr. Cancer Res. 2004 Oct 15;64(20):7570-8. doi: 10.1158/0008-5472.CAN-04-1238. Cancer Res. 2004. PMID: 15492284

5

Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.

Liu X, Yue P, Zhou Z, Khuri FR, Sun SY. Liu X, et al. Among authors: khuri fr. J Natl Cancer Inst. 2004 Dec 1;96(23):1769-80. doi: 10.1093/jnci/djh322. J Natl Cancer Inst. 2004. PMID: 15572759

6

Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells.

Jin F, Liu X, Zhou Z, Yue P, Lotan R, Khuri FR, Chung LW, Sun SY. Jin F, et al. Among authors: khuri fr. Cancer Res. 2005 Jul 15;65(14):6354-63. doi: 10.1158/0008-5472.CAN-04-4061. Cancer Res. 2005. PMID: 16024638

7

Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H, Khuri FR. Sun SY, et al. Among authors: khuri fr. Cancer Res. 2005 Aug 15;65(16):7052-8. doi: 10.1158/0008-5472.CAN-05-0917. Cancer Res. 2005. PMID: 16103051

8

The combination of the farnesyl transferase inhibitor lonafarnib and the proteasome inhibitor bortezomib induces synergistic apoptosis in human myeloma cells that is associated with down-regulation of p-AKT.

David E, Sun SY, Waller EK, Chen J, Khuri FR, Lonial S. David E, et al. Among authors: khuri fr. Blood. 2005 Dec 15;106(13):4322-9. doi: 10.1182/blood-2005-06-2584. Epub 2005 Aug 23. Blood. 2005. PMID: 16118318 Free article.

9

Tumor growth inhibition by simultaneously blocking epidermal growth factor receptor and cyclooxygenase-2 in a xenograft model.

Zhang X, Chen ZG, Choe MS, Lin Y, Sun SY, Wieand HS, Shin HJ, Chen A, Khuri FR, Shin DM. Zhang X, et al. Among authors: khuri fr. Clin Cancer Res. 2005 Sep 1;11(17):6261-9. doi: 10.1158/1078-0432.CCR-04-2102. Clin Cancer Res. 2005. PMID: 16144930

10

Decoy receptor 2 (DcR2) is a p53 target gene and regulates chemosensitivity.

Liu X, Yue P, Khuri FR, Sun SY. Liu X, et al. Among authors: khuri fr. Cancer Res. 2005 Oct 15;65(20):9169-75. doi: 10.1158/0008-5472.CAN-05-0939. Cancer Res. 2005. PMID: 16230375

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