Boulter J - Search Results

1

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.

Dunn SM, Rizkallah PJ, Baston E, Mahon T, Cameron B, Moysey R, Gao F, Sami M, Boulter J, Li Y, Jakobsen BK. Dunn SM, et al. Among authors: boulter j. Protein Sci. 2006 Apr;15(4):710-21. doi: 10.1110/ps.051936406. Protein Sci. 2006. PMID: 16600963 Free PMC article.

2

Stable, soluble T-cell receptor molecules for crystallization and therapeutics.

Boulter JM, Glick M, Todorov PT, Baston E, Sami M, Rizkallah P, Jakobsen BK. Boulter JM, et al. Protein Eng. 2003 Sep;16(9):707-11. doi: 10.1093/protein/gzg087. Protein Eng. 2003. PMID: 14560057

3

Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry.

Sami M, Rizkallah PJ, Dunn S, Molloy P, Moysey R, Vuidepot A, Baston E, Todorov P, Li Y, Gao F, Boulter JM, Jakobsen BK. Sami M, et al. Among authors: boulter jm. Protein Eng Des Sel. 2007 Aug;20(8):397-403. doi: 10.1093/protein/gzm033. Epub 2007 Jul 20. Protein Eng Des Sel. 2007. PMID: 17644531

4

Amplification and one-step expression cloning of human T cell receptor genes.

Moysey R, Vuidepot AL, Boulter JM. Moysey R, et al. Anal Biochem. 2004 Mar 15;326(2):284-6. doi: 10.1016/j.ab.2003.12.011. Anal Biochem. 2004. PMID: 15003572 No abstract available.

5

Directed evolution of human T-cell receptors with picomolar affinities by phage display.

Li Y, Moysey R, Molloy PE, Vuidepot AL, Mahon T, Baston E, Dunn S, Liddy N, Jacob J, Jakobsen BK, Boulter JM. Li Y, et al. Among authors: boulter jm. Nat Biotechnol. 2005 Mar;23(3):349-54. doi: 10.1038/nbt1070. Epub 2005 Feb 20. Nat Biotechnol. 2005. PMID: 15723046

6

Human TCR-binding affinity is governed by MHC class restriction.

Cole DK, Pumphrey NJ, Boulter JM, Sami M, Bell JI, Gostick E, Price DA, Gao GF, Sewell AK, Jakobsen BK. Cole DK, et al. Among authors: boulter jm. J Immunol. 2007 May 1;178(9):5727-34. doi: 10.4049/jimmunol.178.9.5727. J Immunol. 2007. PMID: 17442956

7

T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding.

Cole DK, Dunn SM, Sami M, Boulter JM, Jakobsen BK, Sewell AK. Cole DK, et al. Mol Immunol. 2008 May;45(9):2700-9. doi: 10.1016/j.molimm.2007.12.009. Epub 2008 Feb 19. Mol Immunol. 2008. PMID: 18243322

8

Production of a soluble disulfide bond-linked TCR in the cytoplasm of Escherichia coli trxB gor mutants.

Liddy N, Molloy PE, Bennett AD, Boulter JM, Jakobsen BK, Li Y. Liddy N, et al. Mol Biotechnol. 2010 Jun;45(2):140-9. doi: 10.1007/s12033-010-9250-0. Mol Biotechnol. 2010. PMID: 20143183

9

Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding.

Willcox BE, Gao GF, Wyer JR, O'Callaghan CA, Boulter JM, Jones EY, van der Merwe PA, Bell JI, Jakobsen BK. Willcox BE, et al. Among authors: boulter jm. Protein Sci. 1999 Nov;8(11):2418-23. doi: 10.1110/ps.8.11.2418. Protein Sci. 1999. PMID: 10595544 Free PMC article.

10

Stable, soluble, high-affinity, engineered T cell receptors: novel antibody-like proteins for specific targeting of peptide antigens.

Boulter JM, Jakobsen BK. Boulter JM, et al. Clin Exp Immunol. 2005 Dec;142(3):454-60. doi: 10.1111/j.1365-2249.2005.02929.x. Clin Exp Immunol. 2005. PMID: 16297157 Free PMC article. Review.

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