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Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo.
Cesana D, Ranzani M, Volpin M, Bartholomae C, Duros C, Artus A, Merella S, Benedicenti F, Sergi Sergi L, Sanvito F, Brombin C, Nonis A, Serio CD, Doglioni C, von Kalle C, Schmidt M, Cohen-Haguenauer O, Naldini L, Montini E. Cesana D, et al. Among authors: sergi sergi l. Mol Ther. 2014 Apr;22(4):774-85. doi: 10.1038/mt.2014.3. Epub 2014 Jan 20. Mol Ther. 2014. PMID: 24441399 Free PMC article.
Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches.
Bortolomai I, Sandri M, Draghici E, Fontana E, Campodoni E, Marcovecchio GE, Ferrua F, Perani L, Spinelli A, Canu T, Catucci M, Di Tomaso T, Sergi Sergi L, Esposito A, Lombardo A, Naldini L, Tampieri A, Hollander GA, Villa A, Bosticardo M. Bortolomai I, et al. Among authors: sergi sergi l. Stem Cells Transl Med. 2019 Oct;8(10):1107-1122. doi: 10.1002/sctm.18-0218. Epub 2019 May 29. Stem Cells Transl Med. 2019. PMID: 31140762 Free PMC article.
Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering.
Soldi M, Sergi Sergi L, Unali G, Kerzel T, Cuccovillo I, Capasso P, Annoni A, Biffi M, Rancoita PMV, Cantore A, Lombardo A, Naldini L, Squadrito ML, Kajaste-Rudnitski A. Soldi M, et al. Among authors: sergi sergi l. Mol Ther Methods Clin Dev. 2020 Oct 20;19:411-425. doi: 10.1016/j.omtm.2020.10.009. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 33294490 Free PMC article.
Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders.
Colantuoni M, Jofra Hernandez R, Pettinato E, Basso-Ricci L, Magnani L, Andolfi G, Rigamonti C, Finardi A, Romeo V, Soldi M, Sergi Sergi L, Rocchi M, Scala S, Hoffman HM, Gregori S, Kajaste-Rudnitski A, Sanvito F, Muzio L, Naldini L, Aiuti A, Mortellaro A. Colantuoni M, et al. Among authors: sergi sergi l. Sci Transl Med. 2023 May 31;15(698):eade3856. doi: 10.1126/scitranslmed.ade3856. Epub 2023 May 31. Sci Transl Med. 2023. PMID: 37256935
Scalable GMP-compliant gene correction of CD4+ T cells with IDLV template functionally validated in vitro and in vivo.
Asperti C, Canarutto D, Porcellini S, Sanvito F, Cecere F, Vavassori V, Ferrari S, Rovelli E, Albano L, Jacob A, Sergi Sergi L, Montaldo E, Ferrua F, González-Granado LI, Lougaris V, Badolato R, Finocchi A, Villa A, Radrizzani M, Naldini L. Asperti C, et al. Among authors: sergi sergi l. Mol Ther Methods Clin Dev. 2023 Aug 23;30:546-557. doi: 10.1016/j.omtm.2023.08.020. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37693944 Free PMC article.
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