Zhang H - Search Results

1

Synthesis and biological activity of phospholipase C-resistant analogues of phosphatidylinositol 4,5-bisphosphate.

Zhang H, Xu Y, Zhang Z, Liman ER, Prestwich GD. Zhang H, et al. Among authors: zhang z. J Am Chem Soc. 2006 May 3;128(17):5642-3. doi: 10.1021/ja060621d. J Am Chem Soc. 2006. PMID: 16637624 Free PMC article.

2

Synthesis and biological activity of PTEN-resistant analogues of phosphatidylinositol 3,4,5-trisphosphate.

Zhang H, Markadieu N, Beauwens R, Erneux C, Prestwich GD. Zhang H, et al. J Am Chem Soc. 2006 Dec 27;128(51):16464-5. doi: 10.1021/ja065002j. J Am Chem Soc. 2006. PMID: 17177371 Free PMC article.

3

Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: chemistry, biology, and molecular modeling.

Huang W, Zhang H, Davrazou F, Kutateladze TG, Shi X, Gozani O, Prestwich GD. Huang W, et al. Among authors: zhang h. J Am Chem Soc. 2007 May 23;129(20):6498-506. doi: 10.1021/ja070195b. Epub 2007 May 1. J Am Chem Soc. 2007. PMID: 17469822 Free PMC article.

4

Synthesis and biological activity of phosphatidylinositol-3,4,5-trisphosphorothioate.

Zhang H, Xu Y, Markadieu N, Beauwens R, Erneux C, Prestwich GD. Zhang H, et al. Bioorg Med Chem Lett. 2008 Jan 15;18(2):762-6. doi: 10.1016/j.bmcl.2007.11.041. Epub 2007 Nov 17. Bioorg Med Chem Lett. 2008. PMID: 18060773 Free PMC article.

5

5-Stabilized phosphatidylinositol 3,4,5-trisphosphate analogues bind Grp1 PH, inhibit phosphoinositide phosphatases, and block neutrophil migration.

Zhang H, He J, Kutateladze TG, Sakai T, Sasaki T, Markadieu N, Erneux C, Prestwich GD. Zhang H, et al. Chembiochem. 2010 Feb 15;11(3):388-95. doi: 10.1002/cbic.200900545. Chembiochem. 2010. PMID: 20052709 Free PMC article.

6

Synthesis of cyclic phosphonate analogues of (lyso)phosphatidic acid using a ring-closing metathesis reaction.

Zhang H, Tsukuhara R, Tigyi G, Prestwich GD. Zhang H, et al. J Org Chem. 2006 Aug 4;71(16):6061-6. doi: 10.1021/jo0607919. J Org Chem. 2006. PMID: 16872189

7

Phosphatidylinositol 4,5-bisphosphate regulates inspiratory burst activity in the neonatal mouse preBötzinger complex.

Crowder EA, Saha MS, Pace RW, Zhang H, Prestwich GD, Del Negro CA. Crowder EA, et al. Among authors: zhang h. J Physiol. 2007 Aug 1;582(Pt 3):1047-58. doi: 10.1113/jphysiol.2007.134577. Epub 2007 Jun 28. J Physiol. 2007. PMID: 17599963 Free PMC article.

8

Fluorometric detection of inositol phosphates and the activity of their enzymes with synthetic pores: discrimination of IP7 and IP6 and phytate sensing in complex matrices.

Butterfield SM, Tran DH, Zhang H, Prestwich GD, Matile S. Butterfield SM, et al. Among authors: zhang h. J Am Chem Soc. 2008 Mar 19;130(11):3270-1. doi: 10.1021/ja710186e. Epub 2008 Feb 27. J Am Chem Soc. 2008. PMID: 18302378 No abstract available.

9

Phosphatase-resistant analogues of lysophosphatidic acid: agonists promote healing, antagonists and autotaxin inhibitors treat cancer.

Prestwich GD, Gajewiak J, Zhang H, Xu X, Yang G, Serban M. Prestwich GD, et al. Among authors: zhang h. Biochim Biophys Acta. 2008 Sep;1781(9):588-94. doi: 10.1016/j.bbalip.2008.03.008. Epub 2008 Apr 8. Biochim Biophys Acta. 2008. PMID: 18454946 Free PMC article. Review.

10

A scalable synthesis of the IP7 isomer, 5-PP-Ins(1,2,3,4,6)P5.

Zhang H, Thompson J, Prestwich GD. Zhang H, et al. Org Lett. 2009 Apr 2;11(7):1551-4. doi: 10.1021/ol900149x. Org Lett. 2009. PMID: 19253999 Free PMC article.

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