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TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.
Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D, St George-Hyslop P, Fraser P. Chen F, et al. Among authors: checler f. Nature. 2006 Apr 27;440(7088):1208-12. doi: 10.1038/nature04667. Nature. 2006. PMID: 16641999
Cathepsin D displays in vitro beta-secretase-like specificity.
Chevallier N, Vizzavona J, Marambaud P, Baur CP, Spillantini M, Fulcrand P, Martinez J, Goedert M, Vincent JP, Checler F. Chevallier N, et al. Among authors: checler f. Brain Res. 1997 Mar 7;750(1-2):11-9. doi: 10.1016/s0006-8993(96)01330-3. Brain Res. 1997. PMID: 9098524
279 results