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Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.
Ueki K, Okada T, Hu J, Liew CW, Assmann A, Dahlgren GM, Peters JL, Shackman JG, Zhang M, Artner I, Satin LS, Stein R, Holzenberger M, Kennedy RT, Kahn CR, Kulkarni RN. Ueki K, et al. Among authors: stein r. Nat Genet. 2006 May;38(5):583-8. doi: 10.1038/ng1787. Epub 2006 Apr 23. Nat Genet. 2006. PMID: 16642022
Regulation of the insulin gene by glucose and fatty acids.
Poitout V, Hagman D, Stein R, Artner I, Robertson RP, Harmon JS. Poitout V, et al. Among authors: stein r. J Nutr. 2006 Apr;136(4):873-6. doi: 10.1093/jn/136.4.873. J Nutr. 2006. PMID: 16549443 Free PMC article. Review.
MafB is required for islet beta cell maturation.
Artner I, Blanchi B, Raum JC, Guo M, Kaneko T, Cordes S, Sieweke M, Stein R. Artner I, et al. Among authors: stein r. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3853-8. doi: 10.1073/pnas.0700013104. Epub 2007 Feb 22. Proc Natl Acad Sci U S A. 2007. PMID: 17360442 Free PMC article.
MafA is a dedicated activator of the insulin gene in vivo.
Artner I, Hang Y, Guo M, Gu G, Stein R. Artner I, et al. Among authors: stein r. J Endocrinol. 2008 Aug;198(2):271-9. doi: 10.1677/JOE-08-0063. Epub 2008 May 30. J Endocrinol. 2008. PMID: 18515495 Free PMC article.
3,123 results