García-Martín E - Search Results

1

Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals.

García-Martín E, Martínez C, Ladero JM, Agúndez JA. García-Martín E, et al. Mol Diagn Ther. 2006;10(1):29-40. doi: 10.1007/BF03256440. Mol Diagn Ther. 2006. PMID: 16646575 Review.

2

High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population.

García-Martín E, Martínez C, Ladero JM, Gamito FJ, Agúndez JA. García-Martín E, et al. Eur J Clin Pharmacol. 2001 Apr;57(1):47-9. doi: 10.1007/s002280100264. Eur J Clin Pharmacol. 2001. PMID: 11372590 Clinical Trial.

3

Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk.

Martínez C, García-Martín E, Ladero JM, Sastre J, Garcia-Gamito F, Diaz-Rubio M, Agúndez JA. Martínez C, et al. Carcinogenesis. 2001 Aug;22(8):1323-6. doi: 10.1093/carcin/22.8.1323. Carcinogenesis. 2001. PMID: 11470765

4

CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity.

García-Martín E, Martínez C, Pizarro RM, García-Gamito FJ, Gullsten H, Raunio H, Agúndez JA. García-Martín E, et al. Clin Pharmacol Ther. 2002 Mar;71(3):196-204. doi: 10.1067/mcp.2002.121371. Clin Pharmacol Ther. 2002. PMID: 11907494

5

Influence of cytochrome P450 CYP2C9 genotypes in lung cancer risk.

García-Martín E, Martínez C, Ladero JM, Gamito FJ, Rodriguez-Lescure A, Agúndez JA. García-Martín E, et al. Cancer Lett. 2002 Jun 6;180(1):41-6. doi: 10.1016/s0304-3835(02)00015-0. Cancer Lett. 2002. PMID: 11911968

6

Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy.

Martínez C, García-Martín E, Pizarro RM, García-Gamito FJ, Agúndez JA. Martínez C, et al. Br J Cancer. 2002 Sep 9;87(6):681-6. doi: 10.1038/sj.bjc.6600494. Br J Cancer. 2002. PMID: 12237780 Free PMC article.

7

Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use.

Martínez C, Blanco G, Ladero JM, García-Martín E, Taxonera C, Gamito FG, Diaz-Rubio M, Agúndez JA. Martínez C, et al. Br J Pharmacol. 2004 Jan;141(2):205-8. doi: 10.1038/sj.bjp.0705623. Epub 2004 Jan 5. Br J Pharmacol. 2004. PMID: 14707031 Free PMC article.

8

Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms.

García-Martín E, Martínez C, Tabarés B, Frías J, Agúndez JA. García-Martín E, et al. Clin Pharmacol Ther. 2004 Aug;76(2):119-27. doi: 10.1016/j.clpt.2004.04.006. Clin Pharmacol Ther. 2004. PMID: 15289789

9

The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects.

Martínez C, García-Martín E, Blanco G, Gamito FJ, Ladero JM, Agúndez JA. Martínez C, et al. Br J Clin Pharmacol. 2005 Jan;59(1):62-9. doi: 10.1111/j.1365-2125.2004.02183.x. Br J Clin Pharmacol. 2005. PMID: 15606441 Free PMC article.

10

Polymorphisms of the glutathione S-transferases mu-1 (GSTM1) and theta-1 (GSTT1) and the risk of advanced alcoholic liver disease.

Ladero JM, Martínez C, García-Martin E, Fernández-Arquero M, López-Alonso G, de la Concha EG, Díaz-Rubio M, Agúndez JA. Ladero JM, et al. Scand J Gastroenterol. 2005 Mar;40(3):348-53. doi: 10.1080/00365520510012109. Scand J Gastroenterol. 2005. PMID: 15932176

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