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Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.
Nagahara K, Arikawa T, Oomizu S, Kontani K, Nobumoto A, Tateno H, Watanabe K, Niki T, Katoh S, Miyake M, Nagahata S, Hirabayashi J, Kuchroo VK, Yamauchi A, Hirashima M. Nagahara K, et al. Among authors: hirabayashi j. J Immunol. 2008 Dec 1;181(11):7660-9. doi: 10.4049/jimmunol.181.11.7660. J Immunol. 2008. PMID: 19017954 Free PMC article.
Further evidence by site-directed mutagenesis that conserved hydrophilic residues form a carbohydrate-binding site of human galectin-1.
Hirabayashi J, Kasai K. Hirabayashi J, et al. Glycoconj J. 1994 Oct;11(5):437-42. doi: 10.1007/BF00731280. Glycoconj J. 1994. PMID: 7535135
On the basis of the previous results (Hirabayashi and Kasai (1992) J Biol Chem 266:23648-53), more systematic mutagenesis experiments were performed in order to confirm the concept that conserved hydrophilic residues play a central role. ...
On the basis of the previous results (Hirabayashi and Kasai (1992) J Biol Chem 266:23648-53), more systematic mutagenesis expe …
264 results